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Acta Cytologica Brush Cytology and Biopsy in the Diagnosis of Colorectal Cancer A Comparison Marisa Halpern, M.D., Rivka Gal, M.D., Lea Rath-Wolfson, M.D., Rumelia Koren, M.D., Ruben Weil, M.D., and Arieh Avni, M.D. OBJECTIVE: To determine the usefulness of brush cy- neoplastic lesions on biopsy. Forty cases negative for ma- tology of colorectal lesions as compared to biopsy exami- lignant cells showed 19 adenomas and 21 nonspecific nation. changes in the biopsy exami- STUDY DESIGN: One nation. hundred brushing cytologies CONCLUSION: Colono- We advocate the routine use of and biopsies were performed scopic brushing cytodiagno- brushing endoscopically suspicious on patients who underwent sis is a sensitive technique for colonoscopic examination for the detection of colorectal lesions in conjunction with tissue different symptoms. The cy- cancer. The combination of biopsy to improve diagnostic accuracy. tologic smears were classified brushing cytology and biop- into five cytologic diagnostic sy improves the accuracy of categories. The histologic di- diagnosis. (Acta Cytol agnoses were adenocarcinoma, adenoma and nonneo- 1997;41:628–632) plastic lesion. RESULTS: Twenty-six cases were cytologically positive Keywords: colorectal neoplasms, endoscopy, brush for malignant cells, and all were histologically diagnosed cytology. as adenocarcinoma. Nineteen cases were suspicious for malignancy on cytology; histologically, eight of
Acta Cytologica – Karger
Published: Jan 1, 2011
Keywords: colorectal neoplasms; endoscopy; brush cytology
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