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Cytologic Features of Colonic Adenocarcinoma

Cytologic Features of Colonic Adenocarcinoma Acta Cytologica Differences Between Primary and Metastatic Neoplasms June H. Koizumi, M.D., M.I.A.C., and Deborah S. Schron, M.D. OBJECTIVE: To evaluate cytologic differences between matic, cigar-shaped nuclei; nucleoli; molding of nuclei; primary and metastatic specimens of colonic adenocarci- palisaded or glandular arrangement; and necrosis. Vary- noma. ing states of preservation and degeneration may explain STUDY DESIGN: Fifty colonic brushings of primary many of these differences. (Acta Cytol 1997;41:419– adenocarcinoma of the colon and 50 specimens of 426) metastatic colonic adenocarcinoma were examined. The latter included fine needle as- Keywords: colonic neo- pirates of lung, liver and plasms, adenocarcinoma, other sites and bronchial neoplasm metastasis, as- Metastatic and primary colonic brushings. piration biopsy. adenocarcinomas show a number of RESULTS: In contrast to primary colonic adenocarci- “Tall, dark, and necrotic” significant differences in cytologic nomas, which typically is Ducatman’s pithy char- appearance that are mainly due showed large, hyperchromat- acterization of adenocarci- ic nuclei, many cases of to varying states of preservation and de- noma of the colon. It is metastatic colonic adenocar- one of the few tumors in generation. cinoma showed nuclei with which the morphologic fine, delicate chromatin and appearance is often dis- distinct nuclear membranes. tinctive enough to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Cytologic Features of Colonic Adenocarcinoma

Acta Cytologica , Volume 41 (2): 8 – Jan 1, 2011

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Publisher
Karger
Copyright
© 1997 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000332534
Publisher site
See Article on Publisher Site

Abstract

Acta Cytologica Differences Between Primary and Metastatic Neoplasms June H. Koizumi, M.D., M.I.A.C., and Deborah S. Schron, M.D. OBJECTIVE: To evaluate cytologic differences between matic, cigar-shaped nuclei; nucleoli; molding of nuclei; primary and metastatic specimens of colonic adenocarci- palisaded or glandular arrangement; and necrosis. Vary- noma. ing states of preservation and degeneration may explain STUDY DESIGN: Fifty colonic brushings of primary many of these differences. (Acta Cytol 1997;41:419– adenocarcinoma of the colon and 50 specimens of 426) metastatic colonic adenocarcinoma were examined. The latter included fine needle as- Keywords: colonic neo- pirates of lung, liver and plasms, adenocarcinoma, other sites and bronchial neoplasm metastasis, as- Metastatic and primary colonic brushings. piration biopsy. adenocarcinomas show a number of RESULTS: In contrast to primary colonic adenocarci- “Tall, dark, and necrotic” significant differences in cytologic nomas, which typically is Ducatman’s pithy char- appearance that are mainly due showed large, hyperchromat- acterization of adenocarci- ic nuclei, many cases of to varying states of preservation and de- noma of the colon. It is metastatic colonic adenocar- one of the few tumors in generation. cinoma showed nuclei with which the morphologic fine, delicate chromatin and appearance is often dis- distinct nuclear membranes. tinctive enough to

Journal

Acta CytologicaKarger

Published: Jan 1, 2011

Keywords: colonic neoplasms; adenocarcinoma; neoplasm metastasis; aspiration biopsy

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