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Acta Cytologica Decision Tree Approach Using Morphologic and Morphometric Parameters Vikram Deshpande, M.D., Kusum Kapila, M.D., F.I.A.C., Krovvidi Siva Sai, Ph.D., and Kusum Verma, M.D., M.I.A.C., F.A.M.S. OBJECTIVE: Fine needle aspiration of the thyroid is lim- Keywords: thyroid neoplasms, decision trees, aspi- ited in differentiating hyperplastic nodular goiters from ration cytology. true follicular neoplasms and in separating follicular adenomas from follicular carcinomas. The present study During the last decade, confidence in fine needle as- was done to evaluate if a panel of morphologic and mor- piration (FNA) has grown considerably, and FNA phometric parameters of the thyroid and ploidy status, has emerged as the most accurate diagnostic proce- either alone or in combina- dure in the management tion, would help differentiate of nodular thyroid dis- hyperplastic nodular goiters eases. The percentage of It would be presumptuous to think from follicular adenomas and patients undergoing thy- that the issue of follicular neoplasms carcinomas. roidectomy has decreased STUDY DESIGN: Fine nee- is now closer to a solution.... by 25%, while the yield of dle aspiration smears of 75 cancer in surgically ex- cases classified as follicular cised thyroids has in- neoplasms of the thyroid were studied for morphologic creased from 15%
Acta Cytologica – Karger
Published: Jan 1, 2011
Keywords: thyroid neoplasms; decision trees; aspiration cytology
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