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Acta Cytologica Simulation of Primary Cervical Cancer Screening by the PAPNET System in an Unscreened, High-Risk Community Pamela M. Michelow, M.B.B.Ch. (Witwatersrand), N. Felicity Hlongwane, C.T.(IAC), and Gladwyn Leiman, M.B.B.Ch. (Witwatersrand), F.R.C.Path. (London), F.I.A.C. OBJECTIVE: To evaluate the performance of the nificant abnormalities, including high grade squamous PAPNET system as a primary cervical cancer screening intraepithelial lesions and invasive carcinoma. modality in an unscreened population with a high preva- CONCLUSION: The PAPNET system, which would lence of cervical cancer and probably not be affordable as its precursor lesions. a quality assurance modality STUDY DESIGN: Consecu- only in the public health sec- Automated cervical screening tive cervical smears from tor of this country, was utilizing the PAPNET system 3,106 women, screened and shown to be more than suffi- reported in the usual man- ciently effective as a primary can significantly enhance the ner, were submitted for screening method for the laboratory component of any such analysis by the PAPNET large numbers of women system. The original manual program. likely to undergo cervical screening diagnoses were cancer screening in antici- compared with those ob- pated mass population pro- tained by PAPNET analysis. By inclusion of normal and grams. (Acta Cytol 1997;41:88–92)
Acta Cytologica – Karger
Published: Jan 1, 2011
Keywords: cervix neoplasms; cervical smears; mass screening; PAPNET
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