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New Diagnostic Techniques Applicable to Fine Needle Aspirates

New Diagnostic Techniques Applicable to Fine Needle Aspirates E DITORIAL Acta Cytologica The Journal of Clinical Cytology and Cytopathology New Diagnostic Techniques Applicable to Fine N eedle Aspirates With the introduction of neoadjuvant therapy in the emerged as valuable diagnostic adjuncts, especially treatment of various malignancies, there is a de- in the diagnosis of musculoskeletal tumors and se- mand for correct pretreatment diagnosis. When fine lected non-Hodgkin’s lymphomas. A number of needle aspiration and cytodiagnosis are considered soft tissue sarcoma entities have been found to ex- to be the optimal diagnostic method before the start press diagnostic chromosomal aberrations (Table I). of treatment, the cytodiagnosis must equal that of a Chromosomal analysis is possible to perform on histopathologic examination. Chemotherapy com- fine needle aspirates, although the success rate is 1,2 binations are different for different malignancies, less than that with analysis of tissue samples. Flu- and in case of preoperative radiotherapy, the thera- orescence in situ hybridization (FISH) is better suit- py might be successful enough to make a specific ed to aspirate smears and exfoliative specimens. histologic type diagnosis difficult or impossible on As the genes involved in various diagnostic translo- histopathologic examination of the operative speci- cations have been identified, the possibility of per- men. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

New Diagnostic Techniques Applicable to Fine Needle Aspirates

Acta Cytologica , Volume 42 (6): 2 – Jan 1, 2011

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Publisher
Karger
Copyright
© 1998 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000332160
Publisher site
See Article on Publisher Site

Abstract

E DITORIAL Acta Cytologica The Journal of Clinical Cytology and Cytopathology New Diagnostic Techniques Applicable to Fine N eedle Aspirates With the introduction of neoadjuvant therapy in the emerged as valuable diagnostic adjuncts, especially treatment of various malignancies, there is a de- in the diagnosis of musculoskeletal tumors and se- mand for correct pretreatment diagnosis. When fine lected non-Hodgkin’s lymphomas. A number of needle aspiration and cytodiagnosis are considered soft tissue sarcoma entities have been found to ex- to be the optimal diagnostic method before the start press diagnostic chromosomal aberrations (Table I). of treatment, the cytodiagnosis must equal that of a Chromosomal analysis is possible to perform on histopathologic examination. Chemotherapy com- fine needle aspirates, although the success rate is 1,2 binations are different for different malignancies, less than that with analysis of tissue samples. Flu- and in case of preoperative radiotherapy, the thera- orescence in situ hybridization (FISH) is better suit- py might be successful enough to make a specific ed to aspirate smears and exfoliative specimens. histologic type diagnosis difficult or impossible on As the genes involved in various diagnostic translo- histopathologic examination of the operative speci- cations have been identified, the possibility of per- men.

Journal

Acta CytologicaKarger

Published: Jan 1, 2011

Keywords: aspiration biopsy; diagnostic techniques and procedures; laboratory diagnosis

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