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Acta Cytologica Bronchoalveolar Lavage Fluid Cytology in Patients with Pneumocystis carinii Pneumonia Jan A. Jacobs, M.D., Ph.D., Martin M. Dieleman, M.D., Elisa I. M. Cornelissen, M.T., Enny A. H. Groen, C.T.(IAC), Sjoerd S. Wagenaar, M.D., Ph.D., and Marjolein Drent, M.D., Ph.D. OBJECTIVE: To evaluate bronchoalveolar lavage (BAL) logic findings observed in half the samples from both pa- cytology and organism burden in patients with Pneu- tient groups included the presence of foamy alveolar mocystis carinii pneumonia macrophages, activated lym- (PCP) who were infected phocytes, plasma cells and with the human immunodefi- reactive type II pneumocytes. This study demonstrated a higher ciency virus (HIV) and in Furthermore, a peculiar cell number of P carinii cysts and FACs those with other immunode- type, “nonidentified cell” ficiencies. (NIC), was observed almost in BAL fluid samples from STUDY DESIGN: BAL exclusively in BAL fluid HIV-infected patients.... fluid samples from patients samples from HIV-infected with PCP were selected patients. (HIV-infected patients, n = CONCLUSION: BAL fluid 15; patients with other immunodeficiencies, n = 11). samples from HIV-infected patients with PCP displayed May-Grünwald-Giemsa–stained cytocentrifuge prepa- higher organism burdens as compared to those from pa- rations were evaluated. Foamy alveolar casts (FACs) and tients with other
Acta Cytologica – Karger
Published: Jan 1, 2011
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