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Acta Cytologica Cytologic Diagnosis and Follow-up Dilip Gupta, M.D., M.I.A.C., Vaidehi Kannan, M.D., Gabor Komaromy-Hiller, Ph.D., and Tilde S. Kline, M.D. OBJECTIVE: To study the cytologic criteria for follow- size, shape, cytoplasmic hue and texture, nuclear size and up of mature metaplastic cells within the atypical squa- contour, chromatin pattern and nucleoli. Additionally, mous cells of undetermined specimens were reviewed for significance (ASCUS) cate- hormonal status and inflam- gory. mation. The findings were Both ASCUS-NOS and -M will STUDY DESIGN: Squa- correlated with follow-up ultimately require cytologic, mous epithelial abnormali- data. colposcopic and/or HPV testing.... ties between January 1994 RESULTS: Cells generally and June 1997 at our institu- appeared single or in loose, tion totaled 2,632 and in- monolayered sheets of three cluded squamous carcinoma (1), high grade squamous to seven cells per group. The cells were well demarcated, intraepithelial lesions (278), low grade squamous in- polygonal or oval and ranged from 11 to 30 µ m with traepithelial lesions (875) and ASCUS (1,478). From the cyanophilic or eosinophilic thickened cytoplasm. The ASCUS group, 134 (9.06%) were metaplastic; 89 were round to oval nuclei with slight irregularity showed a selected for review. Criteria for case selection were fol- minimally
Acta Cytologica – Karger
Published: Jan 1, 2011
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