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Comparative Analysis of a Liquid-Based Pap Test and Concurrent HPV DNA Assay of Residual Samples

Comparative Analysis of a Liquid-Based Pap Test and Concurrent HPV DNA Assay of Residual Samples Acta Cytologica Comparative Analysis of a Liquid-Based Pap Test and Concurrent HPV DNA Assay of Residual Samples A Study of 608 Cases In Soon Hong, M.D., Josephine Marshalleck, M.D., Robert H. Williams, M.D., Thomas E. Gaiter, M.D., Iwona Mielzynska-Lohnas, Ph.D., and Kyungsook Kim, Ph.D. OBJECTIVE: To retrospectively study the HPV DNA samples were between 8 days to 10 months old, and each assay of residual samples from the ThinPrep Pap vial contained 4 mL. Of the 608 study cases, 76 were TM Test (Cytyc Corporation, WNL, 115 contained BCC, Boxborough, Massachusetts, 172 contained ASCUS, 179 U.S.A.) PreserveCyt Combination testing is an objective were LSIL and 66 were (Cytyc) vial as a quality im- HSIL. In this study, the 191 and “gold standard” triage method of provement (QI) indicator for WNL and BCC cases were managing ASCUS cytology. management of patients with designated as the disease-free abnormal cervical cytology. control group. The HPV STUDY DESIGN: Six hun- DNA typing results were re- dred eight residual sample vials of liquid-based Pap-Test ported as low-risk, high/intermediate-risk or HPV DNA specimens were selected for the study based on Pap-test “not detected” HPV types. The HPV DNA testing re- results from October 1998 to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Comparative Analysis of a Liquid-Based Pap Test and Concurrent HPV DNA Assay of Residual Samples

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References (19)

Publisher
Karger
Copyright
© 2011 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000327055
Publisher site
See Article on Publisher Site

Abstract

Acta Cytologica Comparative Analysis of a Liquid-Based Pap Test and Concurrent HPV DNA Assay of Residual Samples A Study of 608 Cases In Soon Hong, M.D., Josephine Marshalleck, M.D., Robert H. Williams, M.D., Thomas E. Gaiter, M.D., Iwona Mielzynska-Lohnas, Ph.D., and Kyungsook Kim, Ph.D. OBJECTIVE: To retrospectively study the HPV DNA samples were between 8 days to 10 months old, and each assay of residual samples from the ThinPrep Pap vial contained 4 mL. Of the 608 study cases, 76 were TM Test (Cytyc Corporation, WNL, 115 contained BCC, Boxborough, Massachusetts, 172 contained ASCUS, 179 U.S.A.) PreserveCyt Combination testing is an objective were LSIL and 66 were (Cytyc) vial as a quality im- HSIL. In this study, the 191 and “gold standard” triage method of provement (QI) indicator for WNL and BCC cases were managing ASCUS cytology. management of patients with designated as the disease-free abnormal cervical cytology. control group. The HPV STUDY DESIGN: Six hun- DNA typing results were re- dred eight residual sample vials of liquid-based Pap-Test ported as low-risk, high/intermediate-risk or HPV DNA specimens were selected for the study based on Pap-test “not detected” HPV types. The HPV DNA testing re- results from October 1998 to

Journal

Acta CytologicaKarger

Published: Jan 1, 2011

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