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Acta Cytologica Fine Needle Aspiration Cytology of Pleomorphic Adenoma of the Breast To the Editor: Below we describe the fine needle aspiration (FNA) cytology findings of a pleomorphic adenoma of the breast, correlate the cytology with the histology and highlight the cytologic diagnostic pitfalls. In April 2000, we performed an FNA procedure on a hard, mobile, slightly irregular, nontender mass in the 6 o’clock position in the right breast of a 42-year-old female who had been aware of the Figure 2 Large globule of basement membrane–like lump for 2 years. The lesion had been increasing in mesenchymal material surrounded by a cluster of epithelial cells size during the previous 12 months. A mammo- showing architectural and cytologic atypia (wet-fixed Papanicolaou-stained FNA smear, × 40). gram taken a year earlier had suggested nothing sinister. The preoperative mammograms showed moderately dense, fibroglandular tissue in the right breast with an increase in the density in the lower Papanicolaou-stained smears (Figures 1 and 2). aspect of the breast but nothing overtly suspicious. The epithelial cells were arranged mostly in 3- No other clinical or laboratory abnormalities were dimensional aggregates, but loosely cohesive detected. The lump was excised and the postopera- groups and single,
Acta Cytologica – Karger
Published: Jan 1, 2011
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