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Impact of Liquid-Based Gynecologic Cytology on an HIV-Positive Population

Impact of Liquid-Based Gynecologic Cytology on an HIV-Positive Population Acta Cytologica Impact of Liquid-Based Gynecologic Cytology on an HIV-Positive Population Sharon L. Swierczynski, M.D., Ph.D., Susan Lewis-Chambers, C.T., Jean R. Anderson, M.D., Jean M. Keller, P.A.C., David A. Hinkle, M.S., and Syed Z. Ali, M.D. OBJECTIVE: To examine the imprint of liquid-based cance (ASCUS)/atypical glandular cells of undetermined technologies for cervicovaginal cytology on HIV-positive significance was diagnosed in 15% of the conventional women, who are at high risk smears and 9% of the liquid- for cervical intraepithelial based preparations (P =.02). A more aggressive approach, with neoplasia. In patients with ASCUS di- STUDY DESIGN: We per- agnoses and tissue follow-up immediate colposcopy and biopsy, formed a retrospective search within 7 months, significant may be warranted for all ASCUS of the cytopathology files of SILs were identified in 29% Johns Hopkins Hospital for with conventional smears diagnoses on liquid-based the cervicovaginal cytology and in 65% with liquid- cervicovaginal cytology in of HIV-positive women to based cytology. examine the effect of liquid- HIV-positive women. CONCLUSION: There was based technology on this pop- no statistically significant ulation. difference in the rate of SILs RESULTS: Significant intraepithelial lesions (SILs) between conventional smears and liquid-based cervico- (low grade SIL or greater) were identified http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Impact of Liquid-Based Gynecologic Cytology on an HIV-Positive Population

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Publisher
Karger
Copyright
© 2011 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000326311
Publisher site
See Article on Publisher Site

Abstract

Acta Cytologica Impact of Liquid-Based Gynecologic Cytology on an HIV-Positive Population Sharon L. Swierczynski, M.D., Ph.D., Susan Lewis-Chambers, C.T., Jean R. Anderson, M.D., Jean M. Keller, P.A.C., David A. Hinkle, M.S., and Syed Z. Ali, M.D. OBJECTIVE: To examine the imprint of liquid-based cance (ASCUS)/atypical glandular cells of undetermined technologies for cervicovaginal cytology on HIV-positive significance was diagnosed in 15% of the conventional women, who are at high risk smears and 9% of the liquid- for cervical intraepithelial based preparations (P =.02). A more aggressive approach, with neoplasia. In patients with ASCUS di- STUDY DESIGN: We per- agnoses and tissue follow-up immediate colposcopy and biopsy, formed a retrospective search within 7 months, significant may be warranted for all ASCUS of the cytopathology files of SILs were identified in 29% Johns Hopkins Hospital for with conventional smears diagnoses on liquid-based the cervicovaginal cytology and in 65% with liquid- cervicovaginal cytology in of HIV-positive women to based cytology. examine the effect of liquid- HIV-positive women. CONCLUSION: There was based technology on this pop- no statistically significant ulation. difference in the rate of SILs RESULTS: Significant intraepithelial lesions (SILs) between conventional smears and liquid-based cervico- (low grade SIL or greater) were identified

Journal

Acta Cytologica – Karger

Published: Jan 1, 2011

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