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intraepithelial lesions on follow-up cervical biopsy; of Cytologic Features of High these, 4 showed HSIL with endocervical gland in- volvement. The authors commented that mainte- Grade Squamous nance of cell polarity in HSIL involving endocervical glands is often seen on ThinPrep Pap Tests™. They Intraepithelial Lesions stated that the cytologic feature of loss of cell polarity Involving Endocervical in HSIL involving endocervical glands, previously re- ported on conventional smears, may not be present Glands on Thin-Layer on thin-layer slides. This has not been my experi- ence. Cytology A 2-year retrospective study produced 97 cases of cervical intraepithelial neoplasia (CIN) 3, 52 (54%) of which showed endocervical gland involvement by CIN 3. There were also 6 cases of AIS. The Thin- Prep Pap Tests™ from these cases were reviewed. To the Editors: The architectural features of HSIL involving endo- I read with interest the article by Ozkan and col- cervical glands were similar to those previously re- leagues on glandular lesions of the cervix on thin- ported on conventional smears. A consistent finding layer Pap tests. However, a few clarifications need to of HSIL involving endocervical glands was the loss of be made. The authors commented on the difficulty central
Acta Cytologica – Karger
Published: Jan 1, 2011
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