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FINE NEEDLE ASPIRATION A Cytohistologic Study with Evaluation of Discordant Cases Sanjay Jogai, M.D., Aisha Al-Jassar, M.D., Labiba Temmim, M.D., Pranab Dey, M.D., M.I.A.C., Aaron O. Adesina, F.M.C.P., and Amanguno H. G., F.M.C.P. Objective Conclusion To analyze the diagnostic efficacy of fine needle aspiration FNAC is a safe, sensitive and specific technique in the ini- cytology (FNAC) in the initial evaluation of thyroid nod- tial evaluation of thyroid nodules. A correct cytologic diag- ules, with special emphasis on discrepant cytologic diagnoses. nosis can be achieved in a majority of cases, thus obviating the need for a second surgical Study Design intervention. A careful and A total of 192 thyroid fine diligent search for various cy- Improper sampling and needle aspirates with subse- tologic features and accurate overinterpretation of cytologic quent histopathologic follow- sampling can help in reducing up were analyzed. The cyto- the number of indeterminate, findings can lead to false negative logic diagnoses were divided false positive and false nega- and false positive diagnoses, into 4 categories: positive for tive diagnoses. (Acta Cytol malignancy, negative for ma- 2005;49:483–488) respectively. lignancy, indeterminate for diagnosis and nondiagnostic. Keywords: thyroid neo- The detailed cytologic features were studied along with plasms; thyroid
Acta Cytologica – Karger
Published: Jan 1, 2011
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