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Cytologic Detection of Urinary Tract Tuberculosis

Cytologic Detection of Urinary Tract Tuberculosis LETTERS TO THE EDITORS Multinucleated urothelial cells may be a prominent Cytologic Detection of finding in urine from catheterized patients and in bladder irrigation samples. Diamond shape of the Urinary Tract Tuberculosis cells, fine cytoplasmic vacuolation and large number of nuclei (50 or more) usually indicate that the cells are epithelial in origin rather than histiocytic. Inflammation-related atypia in the urothelial cells may be quite alarming, leading to the erroneous diag- To the Editors: nosis of malignancy. The distinction between atypical Urinary tract tuberculosis is a common disease of de- urothelial cells of tuberculosis and malignant cells has veloping countries like India. Patients usually present been extensively reviewed. Finding granulomas with with frequency, burning sensation and terminal hema- Langhans’ type giant cells and the presence of AFB turia with or without systemic symptoms. Urinary usually points to the correct diagnosis, although in a cytology is used as a screening procedure to detect uri- rare case tuberculosis and malignancy may coexist. nary tract malignancy. Finding granulomatous pa- The presence of well-formed epithelioid cell gran- thology in the urine in such a setting leads to the pre- ulomas in the urine specimen is uncommon. Kapila sumptive diagnosis of tuberculosis, as it http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Cytologic Detection of Urinary Tract Tuberculosis

Adhya, Amit Kumar; Dey, Pranab
Acta Cytologica , Volume 54 (4): 2 – Jan 1, 2011
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References (11)

Publisher
Karger
Copyright
© 2011 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000325195
Publisher site
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Abstract

LETTERS TO THE EDITORS Multinucleated urothelial cells may be a prominent Cytologic Detection of finding in urine from catheterized patients and in bladder irrigation samples. Diamond shape of the Urinary Tract Tuberculosis cells, fine cytoplasmic vacuolation and large number of nuclei (50 or more) usually indicate that the cells are epithelial in origin rather than histiocytic. Inflammation-related atypia in the urothelial cells may be quite alarming, leading to the erroneous diag- To the Editors: nosis of malignancy. The distinction between atypical Urinary tract tuberculosis is a common disease of de- urothelial cells of tuberculosis and malignant cells has veloping countries like India. Patients usually present been extensively reviewed. Finding granulomas with with frequency, burning sensation and terminal hema- Langhans’ type giant cells and the presence of AFB turia with or without systemic symptoms. Urinary usually points to the correct diagnosis, although in a cytology is used as a screening procedure to detect uri- rare case tuberculosis and malignancy may coexist. nary tract malignancy. Finding granulomatous pa- The presence of well-formed epithelioid cell gran- thology in the urine in such a setting leads to the pre- ulomas in the urine specimen is uncommon. Kapila sumptive diagnosis of tuberculosis, as it

Journal

Acta Cytologica – Karger

Published: Jan 1, 2011

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