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Diagnosis of Malignant Granular Cell Tumor Metastatic to Bone by Fine Needle Aspiration Cytology

Diagnosis of Malignant Granular Cell Tumor Metastatic to Bone by Fine Needle Aspiration Cytology Case Reports Diagnosis of Malignant Granular Cell Tumor Metastatic to Bone by Fine Needle Aspiration Cytology A Case Report Anastasia M. Canacci, M.D., Carlos Nunez, M.D., Patrick Getty, M.D., and Fadi Abdul-Karim, M.D. Background ranular cell tumors (GCTs) have been reported to occur at Malignant granular cell tumor (GCT) is a rare sarcoma that is often dif- Gevery site but are most common in the head and neck region, ficult to differentiate histologically from its benign counterpart. especially the tongue, followed by the chest wall and upper extrem- ities. Involvement of multiple sites has been reported in 10–15% of Case patients. Malignant GCTs are rare, accounting for < 2% of all A 69-year-old Caucasian man with a long history of multiple GCTs pre- GCTs. The diagnosis of malignant GCT is generally made when sented with new-onset left shoulder pain and limitation of movement. Ra- regional or distant metastases are present. Histopathologically, diographic studies revealed a lytic primary malignant GCTs usually lesion within the left humeral meta- exhibit cytologic atypia, increased physis and a pathologic fracture. Com- mitoses and necrosis. Metastatic It is indeed difficult, if not impossible, to puted tomography–guided fine needle GCTs most commonly occur in aspiration and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Diagnosis of Malignant Granular Cell Tumor Metastatic to Bone by Fine Needle Aspiration Cytology

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Publisher
Karger
Copyright
© 2011 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000325007
Publisher site
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Abstract

Case Reports Diagnosis of Malignant Granular Cell Tumor Metastatic to Bone by Fine Needle Aspiration Cytology A Case Report Anastasia M. Canacci, M.D., Carlos Nunez, M.D., Patrick Getty, M.D., and Fadi Abdul-Karim, M.D. Background ranular cell tumors (GCTs) have been reported to occur at Malignant granular cell tumor (GCT) is a rare sarcoma that is often dif- Gevery site but are most common in the head and neck region, ficult to differentiate histologically from its benign counterpart. especially the tongue, followed by the chest wall and upper extrem- ities. Involvement of multiple sites has been reported in 10–15% of Case patients. Malignant GCTs are rare, accounting for < 2% of all A 69-year-old Caucasian man with a long history of multiple GCTs pre- GCTs. The diagnosis of malignant GCT is generally made when sented with new-onset left shoulder pain and limitation of movement. Ra- regional or distant metastases are present. Histopathologically, diographic studies revealed a lytic primary malignant GCTs usually lesion within the left humeral meta- exhibit cytologic atypia, increased physis and a pathologic fracture. Com- mitoses and necrosis. Metastatic It is indeed difficult, if not impossible, to puted tomography–guided fine needle GCTs most commonly occur in aspiration and

Journal

Acta Cytologica – Karger

Published: Jan 1, 2011

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