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- Publisher
- Karger
- Copyright
- © 2010 S. Karger AG, Basel
- ISSN
- 0001-5792
- eISSN
- 1421-9662
- DOI
- 10.1159/000313448
- Publisher site
- See Article on Publisher Site
Abstract
Brief Communication Received: November 30, 2009 Acta Haematol 2010;123:226–229 Accepted after revision: February 15, 2010 DOI: 10.1159/000313448 Published online: April 27, 2010 Estimation of Daily Proteinuria in Patients with Multiple Myeloma by Using the Protein-to-Creatinine Ratio in Random Urine Samples a a a b Jocelyn L. Wozney Abdulla A. Damluji Faris Ahmed Maurizio Zangari a a Thomas P. Loughran, Jr. Giampaolo Talamo a b Penn State Hershey Cancer Institute, Hershey, Pa. , University of Utah, Division of Hematology, Blood/Marrow Transplant and Myeloma Program, Salt Lake City, Utah , USA U rine proteins in multiple myeloma (MM) include not discarded because they were found to be incomplete [8] . only monoclonal light chains (‘Bence-Jones’ proteins) but Due to the difficulties involved in obtaining a complete also albumin, which can be excreted in large amounts, sample, results are often inaccurate and unreliable [9, 10] . sometimes in the nephrotic range. A daily excretion Moreover, laboratory manipulation of specimens is cost- 1 12 g is sufficient to define stage III disease in the Durie- ly and relatively time-consuming [11–13] . The use of the Salmon system [1] . The International Myeloma Working random (‘spot’) protein-to-creatinine (Pr/Cr) ratio has Group recommends a 24-hour urine collection
Journal
Acta Haematologica – Karger
Published: Jan 1, 2010