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Heteromorphic Pair of Metacentric Chromosomes with Fused Arms and the Philadelphia Chromosome in a Case of Acute Myeloid Leukemia

Heteromorphic Pair of Metacentric Chromosomes with Fused Arms and the Philadelphia Chromosome in... The cytogenetic studies of a 61-year-old male with an acute myeloid leukemia revealed prior to antileukemic therapy a heteromorphic pair of chromosomes with fused arms and mid-located centromere. Also the and loss of A3, B and G accompanied by gain of D and E members, were consistent karyotypic findings. The karyotypicpattern of different cell lines was suggestive of a common stem cell origin. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

Heteromorphic Pair of Metacentric Chromosomes with Fused Arms and the Philadelphia Chromosome in a Case of Acute Myeloid Leukemia

Khan, M.H.
Acta Haematologica , Volume 48 (5): 8 – Jan 1, 2009
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Publisher
Karger
Copyright
© 1972 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000208476
Publisher site
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Abstract

The cytogenetic studies of a 61-year-old male with an acute myeloid leukemia revealed prior to antileukemic therapy a heteromorphic pair of chromosomes with fused arms and mid-located centromere. Also the and loss of A3, B and G accompanied by gain of D and E members, were consistent karyotypic findings. The karyotypicpattern of different cell lines was suggestive of a common stem cell origin.

Journal

Acta Haematologica – Karger

Published: Jan 1, 2009

Keywords: Acute myeloid leukemia; Chromosome anomalies in leukemia; Karyotype; Marker chromosomes; Ph1 chromosome

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