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Absence of the Y Chromosome in Patients with Chronic Granulocytic Leukaemia

Absence of the Y Chromosome in Patients with Chronic Granulocytic Leukaemia The Y chromosome was missing from the cells of aspirated bone marrow in 2 patients with chronic granulocytic leukaemia (CGL). In both cases, blast cell transformation occurred within 17 months of presentation. Their short course is in contrast to the hypothesis that absence of the Y chromosome in CGL is compatible with long survival. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

Absence of the Y Chromosome in Patients with Chronic Granulocytic Leukaemia

Acta Haematologica , Volume 54 (6): 8 – Jan 1, 1975

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Publisher
Karger
Copyright
© 1975 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000208098
Publisher site
See Article on Publisher Site

Abstract

The Y chromosome was missing from the cells of aspirated bone marrow in 2 patients with chronic granulocytic leukaemia (CGL). In both cases, blast cell transformation occurred within 17 months of presentation. Their short course is in contrast to the hypothesis that absence of the Y chromosome in CGL is compatible with long survival.

Journal

Acta HaematologicaKarger

Published: Jan 1, 1975

Keywords: Chronic granulocytic leukaemia; Karyotype; Y chromosome

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