Relationship of Density Distribution and Pyruvate Kinase Electrophoretic Pattern of Erythrocytes in Sickle Cell Diseases and Other Disorders
Relationship of Density Distribution and Pyruvate Kinase Electrophoretic Pattern of Erythrocytes...
Oda, Susumu; Oda, Etsuko; Tanaka, Kouichi R.
1978-01-01 00:00:00
The density distributions of red cells from sickle cell disorders and other hematological diseases were determined. In sickle cell anemia there was an increase in the proportion of cells in both the heaviest and lightest fractions. In hemoglobin SC disease, a small fraction was shifted to heavier cells. Sickle cell trait blood had a normal density pattern. In hereditary spherocytosis an increase in the number of heavy cells was observed. Thin-layer polyacrylamide gel electrophoresis of red cell pyruvate kinase demonstrated that the pyruvate kinase electrophoretic pattern was related to density distribution.
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngActa HaematologicaKargerhttp://www.deepdyve.com/lp/karger/relationship-of-density-distribution-and-pyruvate-kinase-Ze8xEtqRp0
Relationship of Density Distribution and Pyruvate Kinase Electrophoretic Pattern of Erythrocytes in Sickle Cell Diseases and Other Disorders
The density distributions of red cells from sickle cell disorders and other hematological diseases were determined. In sickle cell anemia there was an increase in the proportion of cells in both the heaviest and lightest fractions. In hemoglobin SC disease, a small fraction was shifted to heavier cells. Sickle cell trait blood had a normal density pattern. In hereditary spherocytosis an increase in the number of heavy cells was observed. Thin-layer polyacrylamide gel electrophoresis of red cell pyruvate kinase demonstrated that the pyruvate kinase electrophoretic pattern was related to density distribution.
Journal
Acta Haematologica
– Karger
Published: Jan 1, 1978
Keywords: Red cell density distribution; Pyruvate kinase electrophoresis; Sickle cell diseases
To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.