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IgG Antiplatelet Antibodies Due to Carbamazepine

IgG Antiplatelet Antibodies Due to Carbamazepine A rare patient with carbamazepine-induced thrombocytopenia is described. Drug-dependent antibodies of the IgG class were detected and characterized by three different techniques: the clot-retraction inhibition test, the platelet-factor 3 immunoinjury technique, and the serotonin release test. The case illustrates the importance of performing the simple and easily available clot-retraction inhibition test in all the patients with thrombocytopenia associated with drugs. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

IgG Antiplatelet Antibodies Due to Carbamazepine

Kornberg, A.; Kobrin, I.
Acta Haematologica , Volume 68 (1): 3 – Jan 1, 1982
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Publisher
Karger
Copyright
© 1982 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000206952
Publisher site
See Article on Publisher Site

Abstract

A rare patient with carbamazepine-induced thrombocytopenia is described. Drug-dependent antibodies of the IgG class were detected and characterized by three different techniques: the clot-retraction inhibition test, the platelet-factor 3 immunoinjury technique, and the serotonin release test. The case illustrates the importance of performing the simple and easily available clot-retraction inhibition test in all the patients with thrombocytopenia associated with drugs.

Journal

Acta Haematologica – Karger

Published: Jan 1, 1982

Keywords: Blood platelets; Carbamazepine; Thrombopenia

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