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Morphology and Genetics in Hereditary Constitutional Anomalies of Leucocytes

Morphology and Genetics in Hereditary Constitutional Anomalies of Leucocytes Proc. 7th Congr. europ. Soc. Haemat., London 1959; Acta haemat. 24: 59-63 (1960). 102 M o rp h o lo g y a n d G enetics in H e r e d ita r y C o n stitu tio n a l A n o m alies o f L eucocytes E . U n d r i t z Pharmacological Laboratories, Sandoz Ltd., Basle, Switzerland T he eight hereditary constitutional anomalies of leucocytes are characterised by peculiarities of form and structure ( U n d r i t z , 1950, 1954). These anomalies are not sex-linked, probably not race-linked and are present unchanged from birth until death ; homozygotic characteristics are more marked than hétérozygotie in the dom inant hereditary anomalies. No difficulties are experienced in classifying heterozygotes and homozygotes according to the known laws of heredity. This is not the case with “ partial carriers of anomaly cells” in dominant anomalies and “ stigmatized individuals” in recessive anomalies. The Dominant Hereditary Anomalies The Pelger-Huêt Anomaly or Pseudo-regenerative While Blood Picture Today 160 families comprising several hundred cases from the white, black and yellow races are known ( U n d r i t z http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

Morphology and Genetics in Hereditary Constitutional Anomalies of Leucocytes

Undritz, E.
Acta Haematologica , Volume 24 (1-3): 5 – Jan 1, 2009
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Publisher
Karger
Copyright
© 1960 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000206446
Publisher site
See Article on Publisher Site

Abstract

Proc. 7th Congr. europ. Soc. Haemat., London 1959; Acta haemat. 24: 59-63 (1960). 102 M o rp h o lo g y a n d G enetics in H e r e d ita r y C o n stitu tio n a l A n o m alies o f L eucocytes E . U n d r i t z Pharmacological Laboratories, Sandoz Ltd., Basle, Switzerland T he eight hereditary constitutional anomalies of leucocytes are characterised by peculiarities of form and structure ( U n d r i t z , 1950, 1954). These anomalies are not sex-linked, probably not race-linked and are present unchanged from birth until death ; homozygotic characteristics are more marked than hétérozygotie in the dom inant hereditary anomalies. No difficulties are experienced in classifying heterozygotes and homozygotes according to the known laws of heredity. This is not the case with “ partial carriers of anomaly cells” in dominant anomalies and “ stigmatized individuals” in recessive anomalies. The Dominant Hereditary Anomalies The Pelger-Huêt Anomaly or Pseudo-regenerative While Blood Picture Today 160 families comprising several hundred cases from the white, black and yellow races are known ( U n d r i t z

Journal

Acta Haematologica – Karger

Published: Jan 1, 2009

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