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Inhibition of Blood Cell Glycolysis in Hypersplenism

Inhibition of Blood Cell Glycolysis in Hypersplenism Vaccari, F ., Traldi, A. a n d Leo, G. C.: A cta h a cm at. 21: 166— 169 (1959). Department of Medical Pathology, University of Modena (Director: Prof. E. St o r t i, M. D.) By F. V a c c a r i ; A. T r a l d i a n d G. C. L e o It has previously been reported (1) th a t a relation exist bet­ ween the anatom ical and functional state o f the bone marrow and the metabolic activity of the peripheral blood cells, since such activity was found to be proportional to the regenerative power of the haemopoietic centres in a high degree. T he lowest metabolic levels were reached by the circulating blood cells in patients suffering from either functional or anatom ical aplasias (1, 2). T h e purpose of this p aper is to report the metabolic findings observed in patients suffering from pure thrombocytopenic purpuras. M aterials and Methods A group of 10 patients was studied who were suffering from thrombocytopenic purpura; 8 of them had idiopathic thrombocytopenic purpura (ITP), cither acute (4 patients) or chronic (4 patients); the remaining 2 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

Inhibition of Blood Cell Glycolysis in Hypersplenism

Acta Haematologica , Volume 21 (3): 4 – Jan 1, 2009

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Publisher
Karger
Copyright
© 1959 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000205668
Publisher site
See Article on Publisher Site

Abstract

Vaccari, F ., Traldi, A. a n d Leo, G. C.: A cta h a cm at. 21: 166— 169 (1959). Department of Medical Pathology, University of Modena (Director: Prof. E. St o r t i, M. D.) By F. V a c c a r i ; A. T r a l d i a n d G. C. L e o It has previously been reported (1) th a t a relation exist bet­ ween the anatom ical and functional state o f the bone marrow and the metabolic activity of the peripheral blood cells, since such activity was found to be proportional to the regenerative power of the haemopoietic centres in a high degree. T he lowest metabolic levels were reached by the circulating blood cells in patients suffering from either functional or anatom ical aplasias (1, 2). T h e purpose of this p aper is to report the metabolic findings observed in patients suffering from pure thrombocytopenic purpuras. M aterials and Methods A group of 10 patients was studied who were suffering from thrombocytopenic purpura; 8 of them had idiopathic thrombocytopenic purpura (ITP), cither acute (4 patients) or chronic (4 patients); the remaining 2

Journal

Acta HaematologicaKarger

Published: Jan 1, 2009

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