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/lp/karger/hodgkin-s-disease-associated-with-chronic-myeloid-leukemia-xSDp7ik6CJ
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- Publisher
- Karger
- Copyright
- © 1994 S. Karger AG, Basel
- ISSN
- 0001-5792
- eISSN
- 1421-9662
- DOI
- 10.1159/000204187
- Publisher site
- See Article on Publisher Site
Abstract
A patient showing lymph node enlargement and tumors in the neck and axilla in the course of Philadelphia (Ph<sup>1</sup>) chromosome-positive chronic myeloid leukemia (CML) was seen. There were no hematological findings suggestive of crisis. RNA was isolated from formalin-fixed and paraffin-embedded tissue specimens for the polymerase chain reaction of bcr-abl. CML-type products were detected in the peripheral blood, but no bcr-abl products were found in the lymph nodes. These findings indicate a very rare case in which Hodgkin’s disease developed during the course of CML.
Journal
Acta Haematologica – Karger
Published: Jan 1, 1994
Keywords: bcr-abl; Chronic myeloid leukemia (CML); Hodgkin’s disease; Ph 1 chromosome; Polymerase chain reaction (PCR)