Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Plasmacytoid CD8 Lymphoma: Morphologic and Immunologic Characterization

Plasmacytoid CD8 Lymphoma: Morphologic and Immunologic Characterization This study describes a 79-year-old female suffering from fever and lymphadenopathy. A lymph node biopsy showed diffuse infiltration of medium-sized cells with plasmacytoid features. The immunologic phenotype determined by cytometric analysis and immunochemistry showed suppressor T antigen (CD2, CD3, CD7, CD8) expression. Absence of CD5 expression characterized this abnormal T cell proliferation, γ T cell receptor rearrangement without immunoglobulin heavy-chain gene rearrangement confirmed the T lineage of these plasmacytoid cells and their clonality. Immunological studies are necessary for identification of this T lymphoma with B microscopic findings. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

Plasmacytoid CD8 Lymphoma: Morphologic and Immunologic Characterization

Loading next page...
 
/lp/karger/plasmacytoid-cd8-lymphoma-morphologic-and-immunologic-characterization-VHRbAlRsic

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Karger
Copyright
© 1995 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000204011
Publisher site
See Article on Publisher Site

Abstract

This study describes a 79-year-old female suffering from fever and lymphadenopathy. A lymph node biopsy showed diffuse infiltration of medium-sized cells with plasmacytoid features. The immunologic phenotype determined by cytometric analysis and immunochemistry showed suppressor T antigen (CD2, CD3, CD7, CD8) expression. Absence of CD5 expression characterized this abnormal T cell proliferation, γ T cell receptor rearrangement without immunoglobulin heavy-chain gene rearrangement confirmed the T lineage of these plasmacytoid cells and their clonality. Immunological studies are necessary for identification of this T lymphoma with B microscopic findings.

Journal

Acta HaematologicaKarger

Published: Jan 1, 1995

Keywords: T lymphoma; Plasmacytoid monocyte; Plasmacytoid T cell

There are no references for this article.