Plasmacytoid CD8 Lymphoma: Morphologic and Immunologic Characterization
Plasmacytoid CD8 Lymphoma: Morphologic and Immunologic Characterization
Amiot, Laurence; Tas, Patrick; Caulet-Maugendre, Sylvie; Goasguen, Jean; Le Prisé, Pierre Yves; Fauchet, Renée; Drenou, Bernard
1995-01-01 00:00:00
This study describes a 79-year-old female suffering from fever and lymphadenopathy. A lymph node biopsy showed diffuse infiltration of medium-sized cells with plasmacytoid features. The immunologic phenotype determined by cytometric analysis and immunochemistry showed suppressor T antigen (CD2, CD3, CD7, CD8) expression. Absence of CD5 expression characterized this abnormal T cell proliferation, γ T cell receptor rearrangement without immunoglobulin heavy-chain gene rearrangement confirmed the T lineage of these plasmacytoid cells and their clonality. Immunological studies are necessary for identification of this T lymphoma with B microscopic findings.
http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.pngActa HaematologicaKargerhttp://www.deepdyve.com/lp/karger/plasmacytoid-cd8-lymphoma-morphologic-and-immunologic-characterization-VHRbAlRsic
Plasmacytoid CD8 Lymphoma: Morphologic and Immunologic Characterization
This study describes a 79-year-old female suffering from fever and lymphadenopathy. A lymph node biopsy showed diffuse infiltration of medium-sized cells with plasmacytoid features. The immunologic phenotype determined by cytometric analysis and immunochemistry showed suppressor T antigen (CD2, CD3, CD7, CD8) expression. Absence of CD5 expression characterized this abnormal T cell proliferation, γ T cell receptor rearrangement without immunoglobulin heavy-chain gene rearrangement confirmed the T lineage of these plasmacytoid cells and their clonality. Immunological studies are necessary for identification of this T lymphoma with B microscopic findings.
Journal
Acta Haematologica
– Karger
Published: Jan 1, 1995
Keywords: T lymphoma; Plasmacytoid monocyte; Plasmacytoid T cell
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