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- Publisher
- Karger
- Copyright
- © 1951 S. Karger AG, Basel
- ISSN
- 0001-5792
- eISSN
- 1421-9662
- DOI
- 10.1159/000203830
- Publisher site
- See Article on Publisher Site
Abstract
Necrología Circulating anticoagulants in hemophilia and in hemophilia-like disease. Singer, K ., M ond, Hyman, Levy. Blood 5, 1135 (1950). Dept. Hem. Research, Michael Reese Hosp. Chicago, 1 1 1 . T he authors stress the importance of distinguishing between hemophilia-like disease (prolonged clotting time and presence of a circulating anticoagulant) and hemophilia complicated by the development of an anticoagulant, following blood transfusion. Two cases with circulating anticoagulants are reported. In one case the anticoagulant was dialyzable and present for a short period of time only. In the second case the presence of hemophilia-like disease or hemophilia plus the anticoagulant was not proved. I t is believed th a t the anticoagulants interfere with the formation of thromboplastin. A simple test for circulating anticoagulants is described. A hemophilia-like disease with prolonged coagulation time and a circulating anticoagulant. Report of a case in a female. Dreskin, O. H ., Rosenthal. Blood 5, 46 (1950). Div. Hem., Mt. Sinai Hospital, New York. T he authors present a case of a female suffering from hemophilia-like disease with a circulating anticoagulant, and propose the name «hemophiloid disease» for th a t syndrome characterized by hemorrhagic manifestations, lengthened coa gulation time and a circulating
Journal
Acta Haematologica – Karger
Published: Jan 1, 2009