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N. Javed, S. Ullah, N. Hussain, M. Sheikh, Ambreen Khan, F. Ghafoor, R. Firdous, Waqar Uddin, Arif Saqib, Ghazal Muhyudin (2017)
Hepatitis E virus seroprevalence in pregnant women in Pakistan: maternal and fetal outcomes.Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 23 8
M. Pérez-Gracia, Beatriz Suay-García, M. Mateos-Lindemann (2017)
Hepatitis E and pregnancy: current stateReviews in Medical Virology, 27
M. Khuroo, S. Kamali, S. Jameel (1995)
Vertical transmission of hepatitis E virusThe Lancet, 345
Hepeviridae -Hepeviridae -Positive-sense RNA Viruses
Meharun-nissa Khaskheli, S. Baloch, A. Sheeba, Sarmad Baloch (2015)
Acute Hepatitis E Viral Infection in Pregnancy and Maternal Morbidity.Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 25 10
Ashok Kumar, S. Devi, P. Kar, S. Agarwal, S. Husain, R. Gupta, Shashi Sharma (2014)
Association of cytokines in hepatitis E with pregnancy outcome.Cytokine, 65 1
Elina Laanto, Sari Mäntynen, Lotta‐Riina Sundberg, A. Kropinski, Evelien Adriaenssens, M. Poranen, H. Oksanen (2020)
Taxonomy proposal 2019: Create one new species Flavobacterium virus FLiP, in the new genus Finnlakevirus, in the new family Finnlakeviridae: ICTV Online: International Committee on Taxonomy of Viruses (ICTV)
Maternal mortality ratio (modeled estimate, per 100,000 live births) | Data [Internet]
T. Yasmeen, H. Hashmi, A. Taj (2013)
Fetomaternal outcome with hepatitis e in pregnancy.Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 23 10
M. Khuroo, M. Khuroo (2008)
Hepatitis E virusCurrent Opinion in Infectious Diseases, 21
Sarman Singh, A. Mohanty, Yogendra Joshi, Sada Dwivedi, Deepika Deka (2001)
Outcome of hepatitis E virus infection in Indian pregnant women admitted to a tertiary care hospital.The Indian journal of medical research, 113
M. Khuroo, M. Teli, S. Skidmore, M. Sofi, M. Khuroo (1981)
Incidence and severity of viral hepatitis in pregnancy.The American journal of medicine, 70 2
R. Purcell, S. Emerson (2008)
Hepatitis E: an emerging awareness of an old disease.Journal of hepatology, 48 3
G. Prasad, Sayi Prasad, A. Bhupali, Ajit Patil, Kanishtha Parashar (2016)
A Study of Hepatitis E in Pregnancy: Maternal and Fetal OutcomeThe Journal of Obstetrics and Gynecology of India, 66
R. Aggarwal, K. Krawczyński (2000)
Hepatitis E: An overview and recent advances in clinical and laboratory researchJournal of Gastroenterology and Hepatology, 15
Namrata Kumar, V. Das, Anjoo Agarwal, A. Pandey, S. Agrawal (2017)
Fetomaternal outcomes in pregnant women with hepatitis E infection; still an important fetomaternal killer with an unresolved mystery of increased virulence in pregnancyTurkish Journal of Obstetrics and Gynecology, 14
NR Shinde, TB Patil, A. Deshpande, RV Gulhane, Mb Patil, YV Bansod (2014)
Clinical Profile, Maternal and Fetal Outcomes of Acute Hepatitis E in PregnancyAnnals of Medical and Health Sciences Research, 4
H Jin, Y Zhao, X Zhang, B Wang, P Liu (2016)
Case‐fatality risk of pregnant women with acute viral hepatitis type E: a systematic review and meta‐analysis. Epidemiology and Infection, 144
M. Khuroo (1980)
Study of an epidemic of non-A, non-B hepatitis. Possibility of another human hepatitis virus distinct from post-transfusion non-A, non-B type.The American journal of medicine, 68 6
(2006)
Association of severity of hepatitis E virus infec ‐ tion in the mother and vertically transmitted infection in the fetus
P. Bose, B. Das, Ashok Kumar, R. Gondal, Deepak Kumar, P. Kar (2011)
High viral load and deregulation of the progesterone receptor signaling pathway: association with hepatitis E-related poor pregnancy outcome.Journal of hepatology, 54 6
S. Devi, Ashok Kumar, P. Kar, S. Husain, Shashi Sharma (2014)
Association of pregnancy outcome with cytokine gene polymorphisms in HEV infection during pregnancyJournal of Medical Virology, 86
Ashok Kumar, B. Beniwal, P. Kar, J. Sharma, N. Murthy (2004)
Hepatitis E in pregnancyInternational Journal of Gynecology & Obstetrics, 85
Rachana Kumar, S. Uduman, S. Rana, J. Kochiyil, A. Usmani, L. Thomas (2001)
Sero-prevalence and mother-to-infant transmission of hepatitis E virus among pregnant women in the United Arab Emirates.European journal of obstetrics, gynecology, and reproductive biology, 100 1
International Committee on Taxonomy of Viruses (ICTV)
Mortality rate, neonatal (per 1,000 live births) | Data [Internet]
P. Christensen, R. Engle, C. Hjort, K. Homburg, W. Vach, J. Georgsen, R. Purcell (2008)
Time trend of the prevalence of hepatitis E antibodies among farmers and blood donors: a potential zoonosis in Denmark.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 47 8
N. Jilani, B. Das, S. Husain, U. Baweja, D. Chattopadhya, R. Gupta, S. Sardana, P. Kar (2007)
Hepatitis E virus infection and fulminant hepatic failure during pregnancyJournal of Gastroenterology and Hepatology, 22
S. Patra, Ashish Kumar, S. Trivedi, M. Puri, S. Sarin (2007)
Maternal and Fetal Outcomes in Pregnant Women with Acute Hepatitis E Virus InfectionAnnals of Internal Medicine, 147
A Bergloev, S Hallager, N Weis
Protocol ‐ Prospero [Internet]
D. Rayis, Ammar Jumaa, G. Gasim, Mubark Karsany, I. Adam (2013)
An outbreak of hepatitis E and high maternal mortality at Port Sudan, Eastern SudanPathogens and Global Health, 107
M. Khuroo, S. Kamili, M. Khuroo (2009)
Clinical course and duration of viremia in vertically transmitted hepatitis E virus (HEV) infection in babies born to HEV‐infected mothersJournal of Viral Hepatitis, 16
L. Scobie, H. Dalton, H. Dalton (2013)
Hepatitis E: source and route of infection, clinical manifestations and new developmentsJournal of Viral Hepatitis, 20
(2018)
Systematic Review and Literature Review Software by Evidence Partners. [cited 2018 Oct 10]. Available from: https ://www.evide ncepa rtners.com
S. Sridhar, J. Teng, T. Chiu, S. Lau, P. Woo (2017)
Hepatitis E Virus Genotypes and Evolution: Emergence of Camel Hepatitis E VariantsInternational Journal of Molecular Sciences, 18
Ila Nimgaonkar, Q. Ding, R. Schwartz, A. Ploss (2018)
Hepatitis E virus: advances and challengesNature Reviews Gastroenterology & Hepatology, 15
Sarman Singh, A. Mohanty, Y. Joshi, D. Deka, S. Mohanty, S. Panda (2003)
Mother-to-child transmission of hepatitis E virus infectionThe Indian Journal of Pediatrics, 70
V. Banait, V. Sandur, F. Parikh, M. Murugesh, Purnima Ranka, V. Ramesh, M. Sasidharan, A. Sattar, S. Kamat, A. Dalal, S. Bhatia (2007)
Outcome of acute liver failure due to acute hepatitis E in pregnant women.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 26 1
Hai-jian Jin, Yueyuan Zhao, Xin-Jiang Zhang, B. Wang, Pei Liu (2016)
Case-fatality risk of pregnant women with acute viral hepatitis type E: a systematic review and meta-analysisEpidemiology and Infection, 144
Protocol ‐ Prospero [ Internet ] Distiller SR [ Internet ] . Systematic Review and Literature Review Software by Evidence Partners
(2018)
Centers for Disease Control and Prevention
(2018)
Protocol ‐ Prospero [Internet]. [cited 2018 Aug 21]. Available from: https ://www.crd.york.ac.uk/prosp ero/displ ay_record.php?Recor dID=100260
Systematic Review and Literature Review Software by Evidence Partners
V. Bhatia, A. Singhal, S. Panda, S. Acharya (2008)
A 20‐year single‐center experience with acute liver failure during pregnancy: Is the prognosis really worse?Hepatology, 48
N. Shrestha, S. Shrestha, A. Singh, K. Malla, L. Thapa (2011)
Maternal and Perinatal Outcome of Pregnancy with Hepatitis E InfectionJournal of Safog With Dvd, 3
Gunjan Bhatnagar, Sheetal Sharma, Ashok Kumar, S. Prasad, S. Agarwal, P. Kar (2016)
Reduced glutathione in hepatitis E infection and pregnancy outcomeJournal of Obstetrics and Gynaecology Research, 42
Mortality rate, neonatal (per 1,000 live births) | Data
Hepatitis E virus infection during pregnancy can have severe consequences for mother and child, such as vertical transmission, fulminant hepatic failure, even foetal or maternal mortality. The aim of this systematic review is to describe maternal, foetal and neonatal case‐fatality rates as well as the prevalence of adverse outcomes in relation to hepatitis E virus infection during pregnancy. A systematic literature search was performed in Pubmed, Embase, Cochrane and CINAHL. Search terms included Pregnant, Women, Maternal, Infant, Foetal, Neonatal and Hepatitis E virus. Data were extracted using predefined data collection forms. All studies were quality assessed, either by the Newcastle‐Ottawa Scale or by an adapted assessment scale for cross‐sectional studies. We found 23 eligible studies, all observational, which were included in this systematic review with a total of 1338 cases. The median maternal, foetal and neonatal case‐fatality rates were 26% (IQR 17%‐41%), 33% (IQR 19%‐37%) and 8% (IQR 3%‐20%), respectively. Adverse outcomes such as fulminant hepatic failure, preterm labour, postpartum haemorrhage, low birth weight and vertical transmission were reported. The two studies that reported the highest prevalence of fulminant hepatic failure also reported the highest case‐fatality rates. The median prevalence of fulminant hepatic failure was 45.3%. This systematic review found a high case‐fatality rate among pregnant women infected with hepatitis E virus and a high rate of adverse outcomes among these women and their children. The results from this review mainly apply to hospital settings and symptomatic pregnant women from endemic countries.
Journal of Viral Hepatitis – Wiley
Published: Nov 1, 2019
Keywords: ; ; ; ;
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