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References (1)
-
D. Mason (1969)
Usefulness and limitations of the rate of rise of intraventricular pressure (dp-dt) in the evaluation of myocardial contractility in man.The American journal of cardiology, 23 4
- Publisher
- Emerald Publishing
- Copyright
- Copyright © Emerald Group Publishing Limited
- ISSN
- 0368-492X
- DOI
- 10.1108/eb005550
- Publisher site
- See Article on Publisher Site
Abstract
Major cardiotonics are now widely used in reviving patients and we are concerned with shock following cardiac surgery. It is, however, difficult to use the most efficient of them, e.g. isoprenalin, with required accuracy regarding its effects. We describe a model which simulates the haemodynamic response to variable doses of cardiotonics. Firstly, one has to identify the parameters of this model and to test it on experimental data. Then one has to use the resulting model in the frame of optimal control of timedependent systems in order to determine some doses nearest the optimum.
Journal
Kybernetes – Emerald Publishing
Published: Feb 1, 1980