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Letters to the Editor Annals of Surgery Volume 274, Number 1, July 2021 superficial, middle, or deepest third of the reliable method, and one we now use, is to REFERENCES submucosa. measure the depth of submucosal invasion in 1. Bolkenstein HE, Consten ECJ, van der Palen J, We had 126 patients with a T1 tumor microns from the deepest portion of the et al., Dutch Diverticular Disease (3D) Collabora- tive Study Group. Long-term outcome of surgery on pathologic re-evaluation, 51 of whom had muscularis mucosa to the bottom of the versus conservative management for recurrent and submucosal tumor invasion (T1b adenocar- tumor. Using this method we found that ongoing complaints after an episode of diverticu- cinoma). The median number of nodes the depth of invasion into the submucosa litis: 5-year follow-up results of a multicenter resected for all patients was 34, with IQ range was only one of the relevant risk factors randomized controlled trial (DIRECT-trial). Ann Surg. 2019;269:612–620. of 21 to 60 nodes. Consequently, these were for node metastases in patients with T1b 2. Klarenbeek BR, Veenhof AA, Bergamaschi R, for the most part extensive lymphadenecto- adenocarcinoma. Other risk factors included et al. Laparoscopic sigmoid resection for
Advances in Nursing Science – Wolters Kluwer Health
Published: Jul 7, 2021
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