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CORR Insights®: Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal Immunogenicity?

CORR Insights®: Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal... Downloaded from http://journals.lww.com/clinorthop by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 Clin Orthop Relat Res (2020) 478:767-769 DOI 10.1097/CORR.0000000000001065 Published online: 26 November 2019 CORR Insights Copyright © 2019 by the Association of Bone and Joint Surgeons CORR Insights®: Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal Immunogenicity? Benjamin K. Potter MD, FACS more common as modern conflict has patients indeed suggests this is not Where Are We Now? progressed from close cannon fire and practical for most patients, and it is not he uncertain hazards of retained musket shot toward armor-piercing worthwhile to try. metallic fragments from inju- rounds, rocket-propelled grenades, and The pilot study by Samelko and Tries sustained in combat are as improvised explosive devices. Medical colleagues [14] found increased lym- old as ballistic conflict itself, and likely advances arising from the recent con- phocyte stimulation indices, increased pre-date gunpowder. Nonetheless, both flicts in Iraq and Afghanistan have in- lymphocyte proliferation index to co- these fragments and their associated creased the survivability of combat balt (in four of 20 fragment patients), hazards have undoubtably become wounds despite increasingly devastat- and generally lower serum immuno- ing injuries [6], resulting in thousands globulin levels in service members of surviving service members with http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Orthopaedics & Related Research Wolters Kluwer Health

CORR Insights®: Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal Immunogenicity?

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Publisher
Wolters Kluwer Health
ISSN
0009-921X
eISSN
1528-1132
DOI
10.1097/CORR.0000000000001065
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Abstract

Downloaded from http://journals.lww.com/clinorthop by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/04/2020 Clin Orthop Relat Res (2020) 478:767-769 DOI 10.1097/CORR.0000000000001065 Published online: 26 November 2019 CORR Insights Copyright © 2019 by the Association of Bone and Joint Surgeons CORR Insights®: Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal Immunogenicity? Benjamin K. Potter MD, FACS more common as modern conflict has patients indeed suggests this is not Where Are We Now? progressed from close cannon fire and practical for most patients, and it is not he uncertain hazards of retained musket shot toward armor-piercing worthwhile to try. metallic fragments from inju- rounds, rocket-propelled grenades, and The pilot study by Samelko and Tries sustained in combat are as improvised explosive devices. Medical colleagues [14] found increased lym- old as ballistic conflict itself, and likely advances arising from the recent con- phocyte stimulation indices, increased pre-date gunpowder. Nonetheless, both flicts in Iraq and Afghanistan have in- lymphocyte proliferation index to co- these fragments and their associated creased the survivability of combat balt (in four of 20 fragment patients), hazards have undoubtably become wounds despite increasingly devastat- and generally lower serum immuno- ing injuries [6], resulting in thousands globulin levels in service members of surviving service members with

Journal

Clinical Orthopaedics & Related Research – Wolters Kluwer Health

Published: Apr 1, 2020

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