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Objective The aim was to conduct a systematic review and meta-analysis analyzing the impact of up to 24 h of prolonged sitting on postprandial glucose, insulin and triglyceride responses, blood pressure and vascular function, in comparison to sitting interrupted with light- to moderate-intensity physical activity. Methods To be included, studies had to examine the impact of prolonged sitting lasting < 24 h in apparently healthy males or females of any age. Studies were identified from searches of the MEDLINE, CINAHL and SportDISCUS databases on July 6, 2016. Study quality was assessed using the Downs and Black Checklist; publication bias was assessed via funnel plot. Results Forty-four studies met the inclusion criteria for the systematic review; of these, 20 were included in the meta- analysis, which compared prolonged sitting to the effects of interrupting sitting with regular activity breaks on postprandial glucose, insulin and triglycerides. When compared to prolonged sitting, regular activity breaks lowered postprandial glu- cose (d = − 0.36, 95% confidence interval [CI] − 0.50 to − 0.21) and insulin (d = − 0.37, 95% CI − 0.53 to − 0.20), but not triglyceride responses (d = 0.06, 95% CI − 0.15 to 0.26). Subgroup analyses indicated reductions in postprandial
Sports Medicine – Springer Journals
Published: Aug 4, 2018
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