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Does patient sex play a role in treatment-free remission in chronic myeloid leukemia?

Does patient sex play a role in treatment-free remission in chronic myeloid leukemia? International Journal of Hematology (2020) 111:903 https://doi.org/10.1007/s12185-020-02864-3 LE T TER TO  THE   EDITOR Does patient sex play a role in treatment‑free remission in chronic myeloid leukemia? 1,2 1,2 1,2 Hiroshi Ureshino  · Kazuharu Kamachi  · Shinya Kimura Received: 16 February 2020 / Revised: 8 March 2020 / Accepted: 11 March 2020 / Published online: 21 March 2020 © Japanese Society of Hematology 2020 Yamaguchi et al. reported treatment-free remission (TFR) Compliance with ethical standards after discontinuation of front-line dasatinib in patients with Conflict of interest S. Kimura received research grants and lecture fees chronic myeloid leukemia (CML) [1]. The TFR appeared to from Bristol-Myers Squibb, Pfizer and Novartis Pharmaceuticals. The be lower than that in recent tyrosine kinase inhibitor (TKI) other authors declare no conflicts of interest (COI). discontinuation studies, especially in studies similar to that of first-line DADI (TFR 55.8% at 1 year) and DASFREE (TFR 54% at 1 year in front-line dasatinib patients) trials [2, References 3]. Although male sex was reportedly a favorable prognostic factor for TFR in the STIM trial, patient sex did not affect 1. Yamaguchi H, Takezako N, Ohashi K, Oba K, Kumagai T, Kozai TFR in the majority of TKI discontinuation trials. The clini- Y, et al. Treatment-free remission http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Hematology Springer Journals

Does patient sex play a role in treatment-free remission in chronic myeloid leukemia?

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Does patient sex play a role in treatment-free remission in chronic myeloid leukemia?

Abstract

International Journal of Hematology (2020) 111:903 https://doi.org/10.1007/s12185-020-02864-3 LE T TER TO  THE   EDITOR Does patient sex play a role in treatment‑free remission in chronic myeloid leukemia? 1,2 1,2 1,2 Hiroshi Ureshino  · Kazuharu Kamachi  · Shinya Kimura Received: 16 February 2020 / Revised: 8 March 2020 / Accepted: 11 March 2020 / Published online: 21 March 2020 © Japanese Society of Hematology 2020...
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References (4)

Publisher
Springer Journals
Copyright
Copyright © Japanese Society of Hematology 2020
ISSN
0925-5710
eISSN
1865-3774
DOI
10.1007/s12185-020-02864-3
Publisher site
See Article on Publisher Site

Abstract

International Journal of Hematology (2020) 111:903 https://doi.org/10.1007/s12185-020-02864-3 LE T TER TO  THE   EDITOR Does patient sex play a role in treatment‑free remission in chronic myeloid leukemia? 1,2 1,2 1,2 Hiroshi Ureshino  · Kazuharu Kamachi  · Shinya Kimura Received: 16 February 2020 / Revised: 8 March 2020 / Accepted: 11 March 2020 / Published online: 21 March 2020 © Japanese Society of Hematology 2020 Yamaguchi et al. reported treatment-free remission (TFR) Compliance with ethical standards after discontinuation of front-line dasatinib in patients with Conflict of interest S. Kimura received research grants and lecture fees chronic myeloid leukemia (CML) [1]. The TFR appeared to from Bristol-Myers Squibb, Pfizer and Novartis Pharmaceuticals. The be lower than that in recent tyrosine kinase inhibitor (TKI) other authors declare no conflicts of interest (COI). discontinuation studies, especially in studies similar to that of first-line DADI (TFR 55.8% at 1 year) and DASFREE (TFR 54% at 1 year in front-line dasatinib patients) trials [2, References 3]. Although male sex was reportedly a favorable prognostic factor for TFR in the STIM trial, patient sex did not affect 1. Yamaguchi H, Takezako N, Ohashi K, Oba K, Kumagai T, Kozai TFR in the majority of TKI discontinuation trials. The clini- Y, et al. Treatment-free remission

Journal

International Journal of Hematology – Springer Journals

Published: Jun 21, 2020

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