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- Publisher
- Springer Journals
- Copyright
- Copyright © 2013 by Springer Science+Business Media New York
- Subject
- Medicine & Public Health; Public Health; Neuropsychology; Neurology; Neuroradiology; Health Psychology
- ISSN
- 1040-7308
- eISSN
- 1573-6660
- DOI
- 10.1007/s11065-013-9235-4
- pmid
- 23904110
- Publisher site
- See Article on Publisher Site
Abstract
Apraxia is one of the cognitive deficits that characterizes Alzheimer’s disease. Despite its prevalence and relevance to diagnosing Alzheimer’s disease, this topic has received little attention and is without comprehensive review. The review herein is aimed to fill this gap by first presenting an overview of the impairment caused in different clinical situations: pantomime of tool use, single tool use, real tool use, mechanical problem solving, function and manipulation knowledge tasks, and symbolic/meaningless gestures. On the basis of these results, we then propose alternative interpretations regarding the nature of the underlying mechanisms impaired by the disease. Also presented are principal methodological issues precluding firm conclusions from being drawn.
Journal
Neuropsychology Review – Springer Journals
Published: Aug 1, 2013