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Impact of valvular resistance on aortic regurgitation after transcatheter aortic valve replacement according to the type of prosthesis

Impact of valvular resistance on aortic regurgitation after transcatheter aortic valve... Background The impact of aortic valvular resistance (VR) on the degree of post-transcatheter aortic valve replacement (TAVR) aortic regurgitation (AR) remains unclear. The objective of the study was to investigate the relationship between VR and paravalvular AR after TAVR. Methods Between August 2007 and December 2015, 708 TAVR patients had sufficient data to calculate VR before the intervention and were eligible for the present analysis. The patient population was dichotomized according to VR. The association between VR and post-TAVR AR was separately assessed by prosthesis type. Results Among patients with low VR (LVR; < 238 dynes/cm ), 176 (49.7%) patients were treated with balloon-expand- able (BE) valves and 178 (51.3%) patients with self-expandable (SE) transcatheter valves. Among patients with high VR (HVR ≥ 238), 147 (41.5%) and 207 (68.5%) patients received BE and SE, respectively. Baseline characteristics were similar in both groups irrespective of the type of valve. Patients with HVR had a 2.5-fold risk of ≥ moderate post-TAVR AR com- pared to patients with LVR. Both, HVR (HR 2.45, 95% CI 1.33–4.51) and the use of SE (HR 3.11, 95% CI 1.66–5.82), adj adj emerged as independent predictors of ≥ moderate post-TAVR AR. Moderate or greater post-AR was http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Zeitschrift für Kardiologie Springer Journals

Impact of valvular resistance on aortic regurgitation after transcatheter aortic valve replacement according to the type of prosthesis

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References (32)

Publisher
Springer Journals
Copyright
Copyright © 2019 by Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Medicine & Public Health; Cardiology
ISSN
0300-5860
eISSN
1861-0692
DOI
10.1007/s00392-019-01469-z
Publisher site
See Article on Publisher Site

Abstract

Background The impact of aortic valvular resistance (VR) on the degree of post-transcatheter aortic valve replacement (TAVR) aortic regurgitation (AR) remains unclear. The objective of the study was to investigate the relationship between VR and paravalvular AR after TAVR. Methods Between August 2007 and December 2015, 708 TAVR patients had sufficient data to calculate VR before the intervention and were eligible for the present analysis. The patient population was dichotomized according to VR. The association between VR and post-TAVR AR was separately assessed by prosthesis type. Results Among patients with low VR (LVR; < 238 dynes/cm ), 176 (49.7%) patients were treated with balloon-expand- able (BE) valves and 178 (51.3%) patients with self-expandable (SE) transcatheter valves. Among patients with high VR (HVR ≥ 238), 147 (41.5%) and 207 (68.5%) patients received BE and SE, respectively. Baseline characteristics were similar in both groups irrespective of the type of valve. Patients with HVR had a 2.5-fold risk of ≥ moderate post-TAVR AR com- pared to patients with LVR. Both, HVR (HR 2.45, 95% CI 1.33–4.51) and the use of SE (HR 3.11, 95% CI 1.66–5.82), adj adj emerged as independent predictors of ≥ moderate post-TAVR AR. Moderate or greater post-AR was

Journal

Zeitschrift für KardiologieSpringer Journals

Published: Mar 30, 2019

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