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Streptococcus pneumoniaeIn Vivo Mouse Models to Study Pneumococcal Host Interaction and Invasive Pneumococcal Disease

Streptococcus pneumoniae: In Vivo Mouse Models to Study Pneumococcal Host Interaction and... [Animal models are fundamental tools to study the biology of physiological processes and disease pathogenesis. To study invasive pneumococcal disease (IPD), many models using mice in particular have been established and developed during recent years. Thanks to the advances of the research in the pneumococcal field, nowadays, there is the possibility to use defined mouse models to study each disease caused by the pneumococcus. In this chapter mouse models for pneumonia, bacteremia, and meningitis are described. Since pneumococci are commensal pathogens found to a high extent in healthy individuals. Hence, we also describe a mouse model for nasopharyngeal colonization.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Streptococcus pneumoniaeIn Vivo Mouse Models to Study Pneumococcal Host Interaction and Invasive Pneumococcal Disease

Part of the Methods in Molecular Biology Book Series (volume 1968)
Editors: Iovino, Federico
Streptococcus pneumoniae — Mar 31, 2019

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References (22)

Publisher
Springer New York
Copyright
© Springer Science+Business Media, LLC, part of Springer Nature 2019
ISBN
978-1-4939-9198-3
Pages
173 –181
DOI
10.1007/978-1-4939-9199-0_14
Publisher site
See Chapter on Publisher Site

Abstract

[Animal models are fundamental tools to study the biology of physiological processes and disease pathogenesis. To study invasive pneumococcal disease (IPD), many models using mice in particular have been established and developed during recent years. Thanks to the advances of the research in the pneumococcal field, nowadays, there is the possibility to use defined mouse models to study each disease caused by the pneumococcus. In this chapter mouse models for pneumonia, bacteremia, and meningitis are described. Since pneumococci are commensal pathogens found to a high extent in healthy individuals. Hence, we also describe a mouse model for nasopharyngeal colonization.]

Published: Mar 31, 2019

Keywords: In vivo; Mouse models; Pneumonia; Meningitis; Invasive pneumococcal disease; Colonization; Coinfection

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