Access the full text.
Sign up today, get DeepDyve free for 14 days.
(2001)
Interstitial deletion of chromosome 11 (q22.3-q23.2) in a boy with mild developmental delay
(2009)
A New York, Mid‐Atlantic guide for patients and health professionals
Martje Pauly, Victor Krajka, Felix Stengel, Philip Seibler, C. Klein, P. Capetian (2018)
Adherent vs. Free-Floating Neural Induction by Dual SMAD Inhibition for Neurosphere Cultures Derived from Human Induced Pluripotent Stem CellsFrontiers in Cell and Developmental Biology, 6
Manasi Talwadekar, Sophia Fernandes, V. Kale, L. Limaye (2016)
Valproic acid enhances the neural differentiation of human placenta derived‐mesenchymal stem cells in vitroJournal of Tissue Engineering and Regenerative Medicine, 11
A. Cole (2012)
GSK3 as a Sensor Determining Cell Fate in the BrainFrontiers in Molecular Neuroscience, 5
P. Pallaki, Eirini-Maria Georganta, Ioannis Serafimidis, M. Papakonstantinou, V. Papanikolaou, Sofia Koutloglou, E. Papadimitriou, Adamantia Agalou, A. Tserga, Alexandra Simeonof, D. Thomaidou, Maria Gaitanou, Z. Georgoussi (2017)
A novel regulatory role of RGS4 in STAT5B activation, neurite outgrowth and neuronal differentiationNeuropharmacology, 117
S. Mathew, D. Head, C. Rodríguez-Galindo, S. Raimondi (2000)
Trisomy of the Long Arm of Chromosome 1 Resulting in a Dicentric Derivative (6)t(1;6) Chromosome in a Child with Myelodysplastic Syndrome Following Treatment for a Primitive Neuroectodermal TumorLeukemia & Lymphoma, 37
I. Kan, E. Melamed, D. Offen, P. Green (2007)
Docosahexaenoic acid and arachidonic acid are fundamental supplements for the induction of neuronal differentiation Published, JLR Papers in Press, December 21, 2006.Journal of Lipid Research, 48
Giwon Kim, Y. Choe, June‐Hee Park, Sehyung Cho, Kyungjin Kim (2002)
Activation of protein kinase A induces neuronal differentiation of HiB5 hippocampal progenitor cells.Brain research. Molecular brain research, 109 1-2
C. Phiel, Fang Zhang, E. Huang, M. Guenther, M. Lazar, P. Klein (2001)
Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen*The Journal of Biological Chemistry, 276
H. Hejr, Majid Ghareghani, K. Zibara, M. Ghafari, Farzad Sadri, Zinab Salehpour, A. Hamedi, K. Negintaji, H. Azari, A. Ghanbari (2017)
The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cellsNeuroscience Letters, 651
I. Kan, E. Melamed, D. Offen, P. Green (2007)
Docosahexaenoic acid and arachidonic acid are fundamental supplements for the induction of neuronal differentiation, 48
(2009)
Developmental‐behavioral pediatrics (4th ed.). Philadelphia, PA: Saunders/Elsevier
C. Bardy, M. Hurk, Boyko Kakaradov, J. Erwin, Baptiste Jaeger, R. Hernandez, Tameji Eames, A. Paucar, M. Gorris, Cynthia Marchand, R. Jappelli, Jerika Barron, A. Bryant, Mariko Kellogg, R. Lasken, B. Rutten, H. Steinbusch, Gene Yeo, Fred Gage (2016)
Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiologyMolecular Psychiatry, 21
M. Obregon, R. Mingarelli, M. Digilio, L. Zelante, A. Giannotti, G. Sabatino, B. Dallapiccola (1992)
Deletion 11q23-->qter (Jacobsen syndrome). Report of three new patients.Annales de genetique, 35 4
Sophia Fernandes, Manasi Talwadekar, Raju Agarwal, V. Nair, V. Kale, L. Limaye (2017)
Generation and characterization of human iPSC line from CD34+ cells isolated from umbilical cord blood belonging to Indian origin.Stem cell research, 18
H. Olson, Y. Shen, A. Poduri, M. Gorman, K. Dies, M. Robbins, R. Hundley, B. Wu, M. Sahin (2012)
Micro-duplications of 1q32.1 associated with neurodevelopmental delay.European journal of medical genetics, 55 2
K. Taysi, G. Sekhon (1978)
Partial trisomy of chromosome no. 1 in two adult brothers due to maternal translocation (1q-;6p+)Human Genetics, 44
L. Menendez, T. Yatskievych, P. Antin, S. Dalton (2011)
Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cellsProceedings of the National Academy of Sciences, 108
E. Hiyama, K. Hiyama, K. Ohtsu, H. Yamaoka, I. Fukuba, Y. Matsuura, T. Yokoyama (2001)
Biological characteristics of neuroblastoma with partial deletion in the short arm of chromosome 1.Medical and pediatric oncology, 36 1
N. Akshoomoff, S. Mattson, P. Grossfeld (2014)
Evidence for autism spectrum disorder in Jacobsen syndrome: identification of a candidate gene in distal 11qGenetics in Medicine, 17
T. Sasaki, M. Okabe, Takeshi Tosaki, Yumiko Honda, M. Ishikawa, N. Tsuboi, T. Yokoo (2018)
Proteinuric glomerulopathy in an adolescent with a distal partial trisomy chromosome 1CEN Case Reports, 7
G. Oyama, R. Rodriguez, H. Fernandez, C. Jacobson, T. Ong, Nelson Hwynn, I. Malaty, M. Okun (2011)
The distal partial trisomy 1q syndrome and dystonic tremor.Parkinsonism & related disorders, 17 2
Yang Sheng, E. Filichia, E. Shick, K. Preston, K. Phillips, Leslie Cooperman, Zhicheng Lin, P. Tesar, B. Hoffer, Yu Luo (2016)
Using iPSC‐derived human DA neurons from opioid‐dependent subjects to study dopamine dynamicsBrain and Behavior, 6
B. Clark, G. Lowther, W. Lee (1994)
Congenital ocular defects associated with an abnormality of the human chromosome 1: trisomy 1q32-qter.Journal of pediatric ophthalmology and strabismus, 31 1
(2020)
Loss of HeterozygosityDefinitions
Stuart Chambers, Christopher Fasano, E. Papapetrou, M. Tomishima, M. Sadelain, L. Studer (2009)
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signalingNature biotechnology, 27
F. Cambosu, G. Capobianco, G. Fogu, P. Bandiera, A. Pirino, M. Moro, R. Sanna, G. Soro, M. Dessole, A. Montella (2013)
Partial trisomy of the long arm of chromosome 1: Prenatal diagnosis, clinical evaluation and cytogenetic findings. Case report and review of the literatureJournal of Obstetrics and Gynaecology Research, 39
A. Duffy, D. Bouchier‐Hayes, J. Harmey (2013)
Vascular Endothelial Growth Factor (VEGF) and Its Role in Non-Endothelial Cells: Autocrine Signalling by VEGF
Isabella Farhy-Tselnicker, N. Allen (2018)
Astrocytes, neurons, synapses: a tripartite view on cortical circuit developmentNeural Development, 13
Dexuan Ma, Minmin Zhang, Christian Larsen, Feng Xu, W. Hua, T. Yamashima, Y. Mao, Liangfu Zhou (2010)
DHA promotes the neuronal differentiation of rat neural stem cells transfected with GPR40 geneBrain Research, 1330
Sophia Fernandes, Shruti Tembe, Prajakta Shinde, Sameer Melinkeri, V. Kale, L. Limaye (2018)
Establishment of human iPSC line NCCSi003-A from CD34+cells of peripheral blood collected during apheresis of healthy donor from Indian ethnicity.Stem cell research, 27
C. Coldren, Z. Lai, P. Shragg, E. Rossi, S. Glidewell, O. Zuffardi, T. Mattina, D. Ivy, L. Curfs, S. Mattson, E. Riley, M. Treier, P. Grossfeld (2009)
Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome)neurogenetics, 10
P. Laeng, R. Pitts, Andrew Lemire, Christopher Drabik, A. Weiner, Haiping Tang, R. Thyagarajan, B. Mallon, C. Altar (2004)
The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cellsJournal of Neurochemistry, 91
T. Dunn, L. Grunfeld, N. Kardon (2001)
Trisomy 1 in a clinically recognized IVF pregnancy.American journal of medical genetics, 99 2
Kateřina Štefková, J. Procházková, J. Pacherník (2015)
Alkaline Phosphatase in Stem CellsStem Cells International, 2015
Juan Yang, Yu Tang, Hui Liu, Fang Guo, Jun Ni, W. Le (2014)
Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cellsBMC Biology, 12
A. Sierra, S. Martín-Suárez, Roberto Valcárcel-Martín, Jesús Pascual-Brazo, Sarah-Ann Aelvoet, Oihane Abiega, J. Deudero, A. Brewster, Irantzu Bernales, A. Anderson, V. Baekelandt, M. Maletić-Savatić, J. Encinas (2015)
Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis.Cell stem cell, 16 5
C. Fong, N. Dracopoli, P. White, P. Merrill, R. Griffith, D. Housman, G. Brodeur (1989)
Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification.Proceedings of the National Academy of Sciences of the United States of America, 86 10
C. Sambani, R. Starza, C. Stavropoulou, K. Manola, N. Harhalakis, C. Mecucci (2002)
A novel dic(1;10) in a patient with myelodysplastic syndrome.Cancer genetics and cytogenetics, 133 1
W. Murphy, L. Frönicke, S. O’Brien, R. Stanyon (2003)
The origin of human chromosome 1 and its homologs in placental mammals.Genome research, 13 8
Sophia Fernandes, Prajakta Shinde, Nikhat Khan, Sanjay Singh, S. Vardhan, V. Nair, V. Kale, L. Limaye (2018)
Derivation of human iPSC line NCCSi002-A from umbilical cord blood (UCB) CD34+cells of donor from Indian ethnicity.Stem cell research, 26
Rajalaxmi Natarajan, V. Singal, Richard Benes, Junling Gao, Hoi Chan, Haijun Chen, Yongjia Yu, Jia Zhou, Ping Wu (2014)
STAT3 Modulation to Enhance Motor Neuron Differentiation in Human Neural Stem CellsPLoS ONE, 9
O. Gorukmez, H. Aydin, S. Sag, A. Kucukcongar, F. Celayir (2015)
MICROARRAY DELINEATION OF DE NOVO DUPLICATION 1q32q42 IN A CHILD SHOWING MULTIPLE ANOMALIES AND DYSMORPHISM.Genetic counseling, 26 2
(2009)
Developmental‐behavioral pediatrics
Christine Wong, Netta Ussyshkin, Eizaaz Ahmad, Ravneet Rai-Bhogal, Hongyan Li, Dorota Crawford (2016)
Prostaglandin E2 promotes neural proliferation and differentiation and regulates Wnt target gene expressionJournal of Neuroscience Research, 94
M. Banzai, Satoshi Sato, H. Matsuda, H. Kanasugi (2004)
Trisomy 1 in a case of a missed abortionJournal of Human Genetics, 49
P. Calder (2016)
Docosahexaenoic AcidAnnals of Nutrition and Metabolism, 69
T. Wardinsky, Edward Weinberger, R. Pagon, S. Clarren, S. Clarren, H. Thuline (1990)
Partial deletion of the long arm of chromosome 11 [del(11)(q23.3----qter)] with abnormal white matter.American journal of medical genetics, 35 1
During the generation of induced pluripotent stem cell (iPSC) lines from cord blood CD34+ cells, a line having complete trisomy of Chromosome 1 and deletion of q23 to qTer of Chromosome 11 was accidentally developed in our lab. The abnormality was consistently detected even at higher passages. These chromosomal anomalies are known to manifest neurological developmental defects. In order to examine if such defects occur during in vitro differentiation of the cell line, we set up a protocol for neural differentiation. Valproic acid (VPA) was earlier reported by us to enhance neural differentiation of placental mesenchymal stem cells. Here, we induced normal and abnormal iPSC lines to neural lineage with/without VPA. Neural differentiation was observed in all four sets, but for both the iPSCs lines, VPA sets performed better. The characteristics tested were morphology, neural filament length, detection of neural markers, and electrophysiology. In summary, the karyotypically abnormal line exhibited efficient neural differentiation. This iPSC line may serve as a useful tool to study abnormalities associated with trisomy 1 and deletion of q23 to qTer of Chromosome 11.
Journal of Tissue Engineering and Regenerative Medicine – Wiley
Published: Aug 1, 2019
Keywords: ; ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.