Access the full text.
Sign up today, get DeepDyve free for 14 days.
Clara Lee, Yuchiao Chang, Nesochi Adimorah, J. Belkora, B. Moy, A. Partridge, D. Ollila, Karen Sepucha (2012)
Decision making about surgery for early-stage breast cancer.Journal of the American College of Surgeons, 214 1
T. Tuttle, E. Habermann, Erin Grund, T. Morris, B. Virnig (2007)
Increasing use of contralateral prophylactic mastectomy for breast cancer patients: a trend toward more aggressive surgical treatment.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 25 33
T. Hurd, S. Edge, M. Kahlenberg, P. Stomper, G. Proulx, G. Schwartz, V. Khatri, J. Winston (1999)
Treatment of early-stage breast cancer.Current problems in cancer, 23 4
M. Raval, K. Bilimoria, A. Stewart, D. Bentrem, C. Ko (2009)
Using the NCDB for cancer care improvement: An introduction to available quality assessment toolsJournal of Surgical Oncology, 99
U. Mahmood, A. Hanlon, M. Koshy, R. Buras, S. Chumsri, K. Tkaczuk, S. Cheston, W. Regine, S. Feigenberg (2013)
Increasing National Mastectomy Rates for the Treatment of Early Stage Breast CancerAnnals of Surgical Oncology, 20
L. Montgomery, K. Tran, Melissa Heelan, K. Zee, M. Massie, D. Payne, P. Borgen (1999)
Issues of Regret in Women With Contralateral Prophylactic MastectomiesAnnals of Surgical Oncology, 6
T. Tuttle, E. Habermann (2011)
Are mastectomies on the rise? A 13-year trend analysis of the selection of mastectomy versus breast conservation therapy in 5865 patientsBreast Diseases: A Year Book Quarterly, 22
A. Dragun, Jianmin Pan, E. Riley, B. Kruse, M. Wilson, S. Rai, D. Jain (2013)
Increasing Use of Elective Mastectomy and Contralateral Prophylactic Surgery Among Breast Conservation Candidates: A 14-year Report From a Comprehensive Cancer CenterAmerican Journal of Clinical Oncology, 36
S. Hawley, R. Jagsi, M. Morrow, N. Janz, A. Hamilton, J. Graff, S. Katz (2014)
Social and Clinical Determinants of Contralateral Prophylactic Mastectomy.JAMA surgery, 149 6
Shoshana Rosenberg, Michaela Tracy, M. Meyer, Karen Sepucha, S. Gelber, J. Hirshfield-Bartek, S. Troyan, M. Morrow, L. Schapira, S. Come, E. Winer, A. Partridge (2013)
Perceptions, Knowledge, and Satisfaction With Contralateral Prophylactic Mastectomy Among Young Women With Breast CancerAnnals of Internal Medicine, 159
J. Barry, T. King (2010)
Trends in Mastectomy Rates at the Mayo Clinic Rochester: Effect of Surgical Year and Preoperative Magnetic Resonance ImagingBreast Diseases: A Year Book Quarterly, 21
B. Fisher, M. Bauer, R. Margolese, R. Poisson, Y. Pilch, C. Redmond, E. Fisher, N. Wolmark, M. Deutsch, E. Montague, E. Saffer, L. Wickerham, H. Lerner, A. Glass, H. Shibata, P. Deckers, A. Ketcham, R. Oishi, I. Russell (1985)
Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer.The New England journal of medicine, 312 11
D. Baumann (2014)
Trends in immediate breast reconstruction across insurance groups after enactment of breast cancer legislationBreast Diseases: A Year Book Quarterly, 25
K. Bilimoria, D. Bentrem, A. Stewart, D. Winchester, C. Ko (2009)
Comparison of commission on cancer-approved and -nonapproved hospitals in the United States: implications for studies that use the National Cancer Data Base.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27 25
C. Garcia-Etienne, M. Tomatis, J. Heil, K. Friedrichs, R. Kreienberg, A. Denk, M. Kiechle, F. Lorenz-Salehi, R. Kimmig, G. Emons, M. Danaei, V. Heyl, U. Heindrichs, C. Rageth, W. Janni, L. Marotti, M. Turco, A. Ponti (2012)
Mastectomy trends for early-stage breast cancer: a report from the EUSOMA multi-institutional European database.European journal of cancer, 48 13
A. Dragun, Bin Huang, T. Tucker, W. Spanos (2012)
Increasing Mastectomy Rates Among all Age Groups for Early Stage Breast Cancer: A 10‐Year Study of Surgical ChoiceThe Breast Journal, 18
U. Veronesi, R. Saccozzi, M. Vecchio, A. Banfi, C. Clemente, M. Lena, G. Gallus, M. Greco, A. Luini, E. Marubini, G. Muscolino, F. Rilke, B. Salvadori, A. Zecchini, R. Zucali (1981)
Comparing Radical Mastectomy with Quadrantectomy, Axillary Dissection, and Radiotherapy in Patients with Small Cancers of the BreastThe New England Journal of Medicine, 305
S. Showalter, S. Grover, Sonam Sharma, L. Lin, B. Czerniecki (2013)
Factors Influencing Surgical and Adjuvant Therapy in Stage I Breast Cancer: A SEER 18 Database AnalysisAnnals of Surgical Oncology, 20
ImportanceAccredited breast centers in the United States are measured on performance of breast conservation surgery (BCS) in the majority of women with early-stage breast cancer. Prior research in regional and limited national cohorts suggests a recent shift toward increasing performance of mastectomy in patients eligible for BCS. ObjectiveTo examine whether mastectomy rates in patients eligible for BCS are increasing over time nationwide, and are associated with coincident increases in breast reconstruction and bilateral mastectomy for unilateral disease. Design, Setting, and ParticipantsWe performed a retrospective cohort study of temporal trends in performance of mastectomy for early-stage breast cancer using multivariable logistic regression modeling to adjust for pertinent covariates and interactions. We studied more than 1.2 million adult women treated at centers accredited by the American Cancer Society and the American College of Surgeons Commission on Cancer from January 1, 1998, to December 31, 2011, using the National Cancer Data Base. ExposuresYear of breast cancer diagnosis. Main Outcomes and MeasuresProportion of women with early-stage breast cancer who underwent mastectomy. Secondary outcome measures include temporal trends in breast reconstruction and bilateral mastectomy for unilateral disease. ResultsA total of 35.5% of the study cohort underwent mastectomy. The adjusted odds of mastectomy in BCS-eligible women increased 34% during the most recent 8 years of the cohort, with an odds ratio of 1.34 (95% CI, 1.31-1.38) in 2011 relative to 2003. Rates of increase were greatest in women with clinically node-negative disease (odds ratio, 1.38; 95% CI, 1.34-1.41) and in situ disease (odds ratio, 2.05; 95% CI, 1.95-2.15). In women undergoing mastectomy, rates of breast reconstruction increased from 11.6% in 1998 to 36.4% in 2011 (P < .001 for trend). Rates of bilateral mastectomy for unilateral disease increased from 1.9% in 1998 to 11.2% in 2011 (P < .001). Conclusions and RelevanceIn the past decade, there have been marked trends toward higher proportions of BCS-eligible patients undergoing mastectomy, breast reconstruction, and bilateral mastectomy. The greatest increases are seen in women with node-negative and in situ disease. Mastectomy rates do not yet exceed current American Cancer Society/American College of Surgeons Commission on Cancer accreditation benchmarks. Further research is needed to understand factors associated with these trends and their implications for performance measurement in American Cancer Society/American College of Surgeons Commission on Cancer centers.
JAMA Surgery – American Medical Association
Published: Jan 1, 2015
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.