Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

New Evidence for Shared Risk Architecture of Mental Disorders

New Evidence for Shared Risk Architecture of Mental Disorders Opinion EDITORIAL New Evidence for Shared Risk Architecture of Mental Disorders Steven E. Hyman, MD In this issue of JAMA Psychiatry, Plana-Ripoll et al provide which includes depressive disorders and bipolar disorder (ICD-10 codes F30-F39), as a single diagnosis, as they did with compelling insights into the frequency, nature, and temporal patterns of comorbidity among mental disorders. Comorbid- each of the other large groupings, such as the schizophrenia ity—the contemporaneous or successive occurrence of at least and related disorders grouping (ICD-10 codes F20-F29) and 1 additional mental disorder neurotic, stress-related, and somatoform disorders grouping given an index diagnosis— (ICD-10 codes F40-48). While the authors state that the deci- Related article page 259 has been well documented sion to use large groupings was based on their need for com- 2 3 by prior research and bedevils clinical practice. What putational tractability, the analysis of comorbidity by broad Plana-Ripoll et al emphatically bring home by analyzing very clusters confers a certain advantage. While the high-level large, high-quality administrative databases is the per- groupings in ICD-10 were never intended to be taken as natu- vasiveness of comorbidity across all domains of psychopa- ral kinds—and certainly do not achieve such status—they are thology. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Psychiatry American Medical Association

New Evidence for Shared Risk Architecture of Mental Disorders

Hyman, Steven E.
JAMA Psychiatry , Volume 76 (3) – Mar 16, 2019
Download PDF
2 pages

Loading next page...
 
/lp/american-medical-association/new-evidence-for-shared-risk-architecture-of-mental-disorders-UD9s2JE8Nh

References (9)

  • V. Anttila, B. Bulik-Sullivan, H. Finucane, R. Walters, J. Bras, L. Duncan, V. Escott-Price, G. Falcone, P. Gormley, R. Malik, N. Patsopoulos, S. Ripke, Zhi Wei, Dongmei Yu, Phil Lee, P. Turley, B. Grenier‐Boley, V. Chouraki, Y. Kamatani, C. Berr, L. Letenneur, D. Hannequin, P. Amouyel, A. Boland, J. Deleuze, E. Duron, B. Vardarajan, C. Reitz, A. Goate, M. Huentelman, M. Kamboh, E. Larson, E. Rogaeva, P. George-Hyslop, H. Hakonarson, W. Kukull, L. Farrer, L. Barnes, T. Beach, F. Demirci, E. Head, C. Hulette, G. Jicha, J. Kauwe, J. Kaye, J. Leverenz, A. Levey, A. Lieberman, V. Pankratz, W. Poon, J. Quinn, A. Saykin, L. Schneider, Amanda Smith, J. Sonnen, R. Stern, V. Deerlin, L. Eldik, D. Harold, G. Russo, D. Rubinsztein, A. Bayer, M. Tsolaki, P. Proitsi, Nick Fox, H. Hampel, M. Owen, S. Mead, P. Passmore, K. Morgan, M. Nöthen, M. Rossor, Michelle Lupton, P. Hoffmann, J. Kornhuber, B. Lawlor, A. McQuillin, A. Al-Chalabi, J. Bis, A. Ruiz, M. Boada, S. Seshadri, A. Beiser, K. Rice, S. Lee, P. Jager, D. Geschwind, M. Riemenschneider, S. Riedel-Heller, J. Rotter, G. Ransmayr, B. Hyman, Carlos Cruchaga, M. Alegret, B. Winsvold, P. Palta, Kai-How Farh, E. Cuenca-León, N. Furlotte, T. Kurth, L. Ligthart, G. Terwindt, T. Freilinger, C. Ran, S. Gordon, G. Borck, H. Adams, T. Lehtimäki, J. Wedenoja, J. Buring, M. Schürks, M. Hrafnsdottir, J. Hottenga, B. Penninx, V. Artto, M. Kaunisto, Salli Vepsäläinen, N. Martin, G. Montgomery, M. Kurki, E. Hämäläinen, Hailiang Huang, Jie Huang, C. Sandor, C. Webber, Bertram Muller-Myhsok, S. Schreiber, V. Salomaa, E. Loehrer, H. Göbel, A. Macaya, P. Pozo‐Rosich, T. Hansen, T. Werge, J. Kaprio, A. Metspalu, C. Kubisch, M. Ferrari, A. Belin, A. Maagdenberg, J. Zwart, D. Boomsma, N. Eriksson, J. Olesen, D. Chasman, D. Nyholt, A. Avbersek, Larry Baum, S. Berkovic, J. Bradfield, R. Buono, C. Catarino, P. Cossette, P. Jonghe, C. Depondt, D. Dlugos, T. Ferraro, J. French, H. Hjalgrim, J. Jamnadas‐Khoda, R. Kälviäinen, W. Kunz, H. Lerche, C. Leu, D. Lindhout, W. Lo, D. Lowenstein, M. McCormack, R. Møller, A. Molloy, P. Ng, Karen Oliver, M. Privitera, R. Radtke, Ann-Kathrin Ruppert, T. Sander, S. Schachter, C. Schankin, I. Scheffer, S. Schoch, S. Sisodiya, P. Smith, M. Sperling, P. Striano, R. Surges, G. Thomas, F. Visscher, C. Whelan, F. Zara, E. Heinzen, A. Marson, F. Becker, H. Stroink, F. Zimprich, T. Gasser, R. Gibbs, P. Heutink, Maria Martinez, H. Morris, M. Sharma, M. Ryten, K. Mok, S. Pulit, S. Bevan, E. Holliday, J. Attia, T. Battey, G. Boncoraglio, V. Thijs, Wei-Min Chen, B. Mitchell, P. Rothwell, Pankaj Sharma, C. Sudlow, A. Vicente, H. Markus, Christina Kourkoulis, J. Pera, Miriam Raffeld, S. Silliman, V. Perica, L. Thornton, L. Huckins, N. Rayner, C. Lewis, M. Gratacós, F. Rybakowski, A. Keski-Rahkonen, A. Raevuori, J. Hudson, T. Reichborn-Kjennerud, P. Monteleone, A. Karwautz, Katrin Mannik, J. Baker, J. O'toole, S. Trace, O. Davis, S. Helder, S. Ehrlich, B. Herpertz-Dahlmann, U. Danner, A. Elburg, M. Clementi, M. Forzan, E. Docampo, J. Lissowska, J. Hauser, A. Tortorella, M. Maj, F. Gonidakis, K. Tziouvas, H. Papežová, Z. Yilmaz, G. Wagner, S. Cohen-Woods, S. Herms, A. Julià, R. Rabionet, D. Dick, S. Ripatti, O. Andreassen, T. Espeseth, A. Lundervold, V. Steen, D. Pinto, S. Scherer, H. Aschauer, A. Schosser, L. Alfredsson, L. Padyukov, K. Halmi, James Mitchell, M. Strober, A. Bergen, W. Kaye, J. Szatkiewicz, B. Cormand, J. Ramos-Quiroga, C. Sánchez-Mora, M. Ribasés, M. Casas, A. Hervás, M. Arranz, J. Haavik, T. Zayats, S. Johansson, N. Williams, A. Dempfle, A. Rothenberger, J. Kuntsi, R. Oades, T. Banaschewski, B. Franke, J. Buitelaar, A. Vásquez, A. Doyle, A. Reif, K. Lesch, C. Freitag, O. Rivero, H. Pálmason, M. Romanos, K. Langley, M. Rietschel, S. Witt, S. Dalsgaard, A. Børglum, I. Waldman, B. Wilmot, N. Molly, Claiton Bau, J. Crosbie, R. Schachar, S. Loo, J. McGough, E. Grevet, S. Medland, E. Robinson, L. Weiss, E. Bacchelli, A. Bailey, V. Bal, A. Battaglia, C. Betancur, P. Bolton, R. Cantor, Patrícia Celestino-Soper, G. Dawson, Silvia Rubeis, F. Duque, A. Green, S. Klauck, M. Leboyer, P. Levitt, E. Maestrini, S. Mane, Daniel De-Luca, J. Parr, R. Regan, A. Reichenberg, S. Sandin, J. Vorstman, T. Wassink, E. Wijsman, E. Cook, S. Santangelo, R. Delorme, B. Rogé, T. Magalhães, D. Arking, T. Schulze, Robert Thompson, J. Strohmaier, K. Matthews, I. Melle, D. Morris, D. Blackwood, A. McIntosh, Sarah Bergen, M. Schalling, S. Jamain, A. Maaser, S. Fischer, C. Reinbold, J. Fullerton, J. Guzmán-Parra, F. Mayoral, P. Schofield, S. Cichon, Thomas Mühleisen, F. Degenhardt, J. Schumacher, M. Bauer, P. Mitchell, E. Gershon, J. Rice, J. Potash, P. Zandi, N. Craddock, I. Ferrier, M. Alda, G. Rouleau, G. Turecki, R. Ophoff, C. Pato, A. Anjorin, E. Stahl, M. Leber, P. Czerski, C. Cruceanu, I. Jones, D. Posthuma, Till Andlauer, A. Forstner, F. Streit, B. Baune, Tracy Air, Grant Sinnamon, N. Wray, D. Macintyre, D. Porteous, G. Homuth, M. Rivera, J. Grove, C. Middeldorp, I. Hickie, M. Pergadia, D. Mehta, J. Smit, R. Jansen, E. Geus, E. Dunn, Qingqin Li, M. Nauck, R. Schoevers, A. Beekman, J. Knowles, A. Viktorin, P. Arnold, C. Barr, Gabriel Bedoya-Berrío, O. Bienvenu, H. Brentani, C. Burton, B. Camarena, C. Cappi, D. Cath, M. Cavallini, D. Cusi, S. Darrow, D. Denys, E. Derks, A. Dietrich, T. Fernandez, M. Figee, N. Freimer, G. Gerber, M. Grados, E. Greenberg, G. Hanna, A. Hartmann, Matthew Hirschtritt, P. Hoekstra, A. Huang, C. Huyser, C. Illmann, M. Jenike, S. Kuperman, B. Leventhal, C. Lochner, G. Lyon, F. Macciardi, M. Madruga‐Garrido, I. Malaty, A. Maras, L. McGrath, E. Miguel, P. Mir, G. Nestadt, H. Nicolini, M. Okun, A. Pakstis, P. Paschou, J. Piacentini, C. Pittenger, K. Plessen, V. Ramensky, E. Ramos, V. Reus, M. Richter, M. Riddle, M. Robertson, V. Roessner, M. Rosário, J. Samuels, P. Sandor, Dan Stein, Fotis Tsetsos, F. Nieuwerburgh, Sarah Weatherall, J. Wendland, T. Wolańczyk, Y. Worbe, G. Zai, F. Goes, N. McLaughlin, P. Nestadt, H. Grabe, C. Depienne, A. Konkashbaev, N. Lanzagorta, A. Valencia-Duarte, E. Bramon, N. Buccola, W. Cahn, M. Cairns, S. Chong, D. Cohen, B. Crespo-Facorro (2018)

    Analysis of shared heritability in common disorders of the brain

    Science, 360

  • C. Maibing, C. Pedersen, M. Benros, P. Mortensen, S. Dalsgaard, M. Nordentoft (2015)

    Risk of Schizophrenia Increases After All Child and Adolescent Psychiatric Disorders: A Nationwide Study.

    Schizophrenia bulletin, 41 4

  • S. Hyman (2010)

    The diagnosis of mental disorders: the problem of reification.

    Annual review of clinical psychology, 6

  • O. Plana-Ripoll, C. Pedersen, Y. Holtz, M. Benros, S. Dalsgaard, P. Jonge, C. Fan, L. Degenhardt, A. Ganna, A. Greve, J. Gunn, K. Iburg, L. Kessing, Brian Lee, C. Lim, O. Mors, M. Nordentoft, Anders Prior, A. Roest, S. Saha, A. Schork, James Scott, K. Scott, T. Stedman, H. Sørensen, T. Werge, H. Whiteford, T. Laursen, E. Agerbo, R. Kessler, P. Mortensen, J. Mcgrath (2019)

    Exploring Comorbidity Within Mental Disorders Among a Danish National Population

    JAMA Psychiatry, 76

  • R. Kotov, Robert Krueger, D. Watson, Thomas Achenbach, Robert Althoff, Michael Bagby, Timothy Brown, Anna Docherty, Joshua Miller, L. Simms, Susan South, J. Tackett (2017)

    The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies

    Journal of Abnormal Psychology, 126

  • R. Kessler, J. Ormel, M. Petukhova, K. McLaughlin, J. Green, L. Russo, Dan Stein, A. Zaslavsky, S. Aguilar-Gaxiola, J. Alonso, L. Andrade, C. Benjet, G. Girolamo, R. Graaf, K. Demyttenaere, J. Fayyad, J. Haro, Chi‐yi Hu, A. Karam, Sing Lee, J. Lépine, Herbert Matchsinger, C. Mihăescu-Pinția, J. Posada-Villa, R. Sagar, T. Ustün (2011)

    Development of lifetime comorbidity in the World Health Organization world mental health surveys.

    Archives of general psychiatry, 68 1

  • K. Kendler, S. Aggen, G. Knudsen, E. Røysamb, M. Neale, T. Reichborn-Kjennerud (2011)

    The structure of genetic and environmental risk factors for syndromal and subsyndromal common DSM-IV axis I and all axis II disorders.

    The American journal of psychiatry, 168 1

  • R. Krueger (1999)

    The structure of common mental disorders.

    Archives of general psychiatry, 56 10

  • R. Kessler, W. Chiu, Olga Demler, K. Merikangas, E. Walters (2005)

    Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.

    Archives of general psychiatry, 62 6

Publisher
American Medical Association
Copyright
Copyright 2019 American Medical Association. All Rights Reserved.
ISSN
2168-622X
eISSN
2168-6238
DOI
10.1001/jamapsychiatry.2018.4269
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL New Evidence for Shared Risk Architecture of Mental Disorders Steven E. Hyman, MD In this issue of JAMA Psychiatry, Plana-Ripoll et al provide which includes depressive disorders and bipolar disorder (ICD-10 codes F30-F39), as a single diagnosis, as they did with compelling insights into the frequency, nature, and temporal patterns of comorbidity among mental disorders. Comorbid- each of the other large groupings, such as the schizophrenia ity—the contemporaneous or successive occurrence of at least and related disorders grouping (ICD-10 codes F20-F29) and 1 additional mental disorder neurotic, stress-related, and somatoform disorders grouping given an index diagnosis— (ICD-10 codes F40-48). While the authors state that the deci- Related article page 259 has been well documented sion to use large groupings was based on their need for com- 2 3 by prior research and bedevils clinical practice. What putational tractability, the analysis of comorbidity by broad Plana-Ripoll et al emphatically bring home by analyzing very clusters confers a certain advantage. While the high-level large, high-quality administrative databases is the per- groupings in ICD-10 were never intended to be taken as natu- vasiveness of comorbidity across all domains of psychopa- ral kinds—and certainly do not achieve such status—they are thology.

Journal

JAMA Psychiatry – American Medical Association

Published: Mar 16, 2019

There are no references for this article.