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Prenatal Ultrasonography and the Incidence of Autism Spectrum Disorder

Prenatal Ultrasonography and the Incidence of Autism Spectrum Disorder Editorial Opinion Prenatal Ultrasonography and the Incidence of Autism Spectrum Disorder Sara Jane Webb, PhD; Pierre D. Mourad, PhD Autismspectrumdisorder(ASD)isabehaviorallydiagnoseddis- safety (time-weighted mean depth of ultrasonography expo- order reflecting clinically significant and persistent impairments sure). The authors found that children with ASD (compared in social communication and restricted and repetitive behaviors, with typically developed children) had fewer first-trimester interests, and activities. Au- scans, a later-date first-trimester scan, lower total mean time tism spectrum disorder is a of exposure in the first and second trimester, increased mean heterogeneous disorder, with depth of ultrasound exposure, and indistinguishable values of Related article page 336 mechanical index and thermal index. In the context of this re- variability in severity of im- pairment, intellectual, and port, mean depth of ultrasound exposure may have several in- language ability and comorbid behavioral and medical concerns. terpretations: (1) it could represent less exposure of the fetus Thediagnosticcategoryhasundergonehistoricalshiftsovertime, to ultrasound because ultrasonography attenuates as it propa- changingtheboundariesofinclusionandcategorization.Asnoted gates, and a larger propagation distance for children with ASD by Chaste et al, our understanding of the etiology of ASD is com- would mean less exposure in utero (all else being equal); or (2) plex and has also evolved through http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Prenatal Ultrasonography and the Incidence of Autism Spectrum Disorder

Webb, Sara Jane; Mourad, Pierre D.
JAMA Pediatrics , Volume 172 (4) – Apr 12, 2018
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References (17)

Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2017.5685
Publisher site
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Abstract

Editorial Opinion Prenatal Ultrasonography and the Incidence of Autism Spectrum Disorder Sara Jane Webb, PhD; Pierre D. Mourad, PhD Autismspectrumdisorder(ASD)isabehaviorallydiagnoseddis- safety (time-weighted mean depth of ultrasonography expo- order reflecting clinically significant and persistent impairments sure). The authors found that children with ASD (compared in social communication and restricted and repetitive behaviors, with typically developed children) had fewer first-trimester interests, and activities. Au- scans, a later-date first-trimester scan, lower total mean time tism spectrum disorder is a of exposure in the first and second trimester, increased mean heterogeneous disorder, with depth of ultrasound exposure, and indistinguishable values of Related article page 336 mechanical index and thermal index. In the context of this re- variability in severity of im- pairment, intellectual, and port, mean depth of ultrasound exposure may have several in- language ability and comorbid behavioral and medical concerns. terpretations: (1) it could represent less exposure of the fetus Thediagnosticcategoryhasundergonehistoricalshiftsovertime, to ultrasound because ultrasonography attenuates as it propa- changingtheboundariesofinclusionandcategorization.Asnoted gates, and a larger propagation distance for children with ASD by Chaste et al, our understanding of the etiology of ASD is com- would mean less exposure in utero (all else being equal); or (2) plex and has also evolved through

Journal

JAMA Pediatrics – American Medical Association

Published: Apr 12, 2018

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