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Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment

Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment Letters To summarize, partner’s acetaminophen use was signifi- cording to Table 2. This Table has n values greater than 8000, cantly associated with childhood behavioral problems and un- substantially greater than population studied (7796). affected by maternal prenatal use. In fact, the effect that part- Overall advice from pharmacologists, neuroscientists, and ner and maternal prenatal use had on the other’s association clinicians invited to comment by Australian media was that this with behavioral problems was mutually positive. Even mater- article should not change current use of acetaminophen dur- nal postnatal use positively affected the association of mater- ing pregnancy. In light of the limitations of this study, such ad- nal prenatal acetaminophen use. Indeed, the findings show an vice seems eminently reasonable. increased risk of behavioral problems in children of mothers using acetaminophen prenatally and postnatally as well as in Norman R. Saunders, MBBS, PhD children of a mother whose partner used acetaminophen. Mark D. Habgood, MSc, PhD Therefore, the authors inaccurately reported their results by Author Affiliations: Department of Pharmacology and Therapeutics, University stating that no associations were found from postnatal or part- of Melbourne, Parkville, Victoria, Australia (Saunders); University of Melbourne, ner’s use and failed to reject http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment

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References (3)

Publisher
American Medical Association
Copyright
Copyright 2017 American Medical Association. All Rights Reserved.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2016.5046
pmid
28192549
Publisher site
See Article on Publisher Site

Abstract

Letters To summarize, partner’s acetaminophen use was signifi- cording to Table 2. This Table has n values greater than 8000, cantly associated with childhood behavioral problems and un- substantially greater than population studied (7796). affected by maternal prenatal use. In fact, the effect that part- Overall advice from pharmacologists, neuroscientists, and ner and maternal prenatal use had on the other’s association clinicians invited to comment by Australian media was that this with behavioral problems was mutually positive. Even mater- article should not change current use of acetaminophen dur- nal postnatal use positively affected the association of mater- ing pregnancy. In light of the limitations of this study, such ad- nal prenatal acetaminophen use. Indeed, the findings show an vice seems eminently reasonable. increased risk of behavioral problems in children of mothers using acetaminophen prenatally and postnatally as well as in Norman R. Saunders, MBBS, PhD children of a mother whose partner used acetaminophen. Mark D. Habgood, MSc, PhD Therefore, the authors inaccurately reported their results by Author Affiliations: Department of Pharmacology and Therapeutics, University stating that no associations were found from postnatal or part- of Melbourne, Parkville, Victoria, Australia (Saunders); University of Melbourne, ner’s use and failed to reject

Journal

JAMA PediatricsAmerican Medical Association

Published: Apr 13, 2017

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