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A Child With Bullous Skin Lesions

A Child With Bullous Skin Lesions Clinical Review & Education JAMA Pediatrics Clinical Challenge Giulia Paloni, MD; Alison Shardlow, MD; Massimo Maschio, MD; Irene Berti, MD; Andrea Taddio, MD; Alessandro Ventura, MD Figure. Rosette-like blisters around a central crust. A 5-year-old girl presented with a 2-week history of pruritic, bullous WHAT IS YOUR DIAGNOSIS? skin lesions that had started on her lower limbs. She had been treated with topical mupirocin and oral amoxicillin–clavulanate potassium for A. Herpetiform dermatitis a suspected superficial skin infection. She B. Pemphigus presented for evaluation because new le- Quiz at jamapediatrics.com sionsofsimilarappearanceappearedonthe C. Linear IgA dermatosis upper limbs, trunk, vulva, and perineum despite antibiotic therapy. D. Erythema multiforme Physical examination revealed many large, tense bullae filled with clear fluid, rounded with an erythematous base and “rosette-like” blisters (Figure). Some of them appeared superinfected. Also the vulva and perineum had an intense erythematous rash. She was apyretic and vi- tal parameters were normal. Laboratory tests showed a normal white blood cell count and lymphocyte subpopulations, erythrocyte sedi- mentation rate, and C-reactive protein level. Test results for anti- transglutaminase and antiendomysial antibodies were negative. jamapediatrics.com JAMA Pediatrics October 2013 Volume 167, Number 10 975 Clinical Review & Education JAMA Pediatrics Clinical Challenge large http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Pediatrics American Medical Association

A Child With Bullous Skin Lesions

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References (8)

Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6203
eISSN
2168-6211
DOI
10.1001/jamapediatrics.2013.2565
pmid
24100394
Publisher site
See Article on Publisher Site

Abstract

Clinical Review & Education JAMA Pediatrics Clinical Challenge Giulia Paloni, MD; Alison Shardlow, MD; Massimo Maschio, MD; Irene Berti, MD; Andrea Taddio, MD; Alessandro Ventura, MD Figure. Rosette-like blisters around a central crust. A 5-year-old girl presented with a 2-week history of pruritic, bullous WHAT IS YOUR DIAGNOSIS? skin lesions that had started on her lower limbs. She had been treated with topical mupirocin and oral amoxicillin–clavulanate potassium for A. Herpetiform dermatitis a suspected superficial skin infection. She B. Pemphigus presented for evaluation because new le- Quiz at jamapediatrics.com sionsofsimilarappearanceappearedonthe C. Linear IgA dermatosis upper limbs, trunk, vulva, and perineum despite antibiotic therapy. D. Erythema multiforme Physical examination revealed many large, tense bullae filled with clear fluid, rounded with an erythematous base and “rosette-like” blisters (Figure). Some of them appeared superinfected. Also the vulva and perineum had an intense erythematous rash. She was apyretic and vi- tal parameters were normal. Laboratory tests showed a normal white blood cell count and lymphocyte subpopulations, erythrocyte sedi- mentation rate, and C-reactive protein level. Test results for anti- transglutaminase and antiendomysial antibodies were negative. jamapediatrics.com JAMA Pediatrics October 2013 Volume 167, Number 10 975 Clinical Review & Education JAMA Pediatrics Clinical Challenge large

Journal

JAMA Pediatrics – American Medical Association

Published: Oct 1, 2013

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