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- Publisher
- American Medical Association
- Copyright
- Copyright 2017 American Medical Association. All Rights Reserved.
- ISSN
- 2168-6181
- eISSN
- 2168-619X
- DOI
- 10.1001/jamaoto.2017.0548
- Publisher site
- See Article on Publisher Site
Abstract
Key PointsQuestionIn oral cavity squamous cell carcinoma (OCSCC), is there an association between specific margin distances and local recurrence, and what should be considered a “close” margin? FindingsIn this retrospective cohort study of 432 patients with OCSCC, there was no appreciable difference between local recurrence rates for different margin distances of 1 mm or greater. Regardless of the specific margin distance, resection of additional tissue after a positive frozen section margin did not significantly alter local recurrence rate. MeaningA cutoff of less than 1 mm between cut tissue edge and invasive tumor would be appropriate to consider as a close margin at risk for recurrence.
Journal
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: Dec 26, 2017