Access the full text.
Sign up today, get DeepDyve free for 14 days.
S. Qian, S. Qian, C. Malata, C. Malata (2014)
Avoiding pitfalls in open augmentation rhinoplasty with autologous L-shaped costal cartilage strut grafts for saddle nose collapse due to autoimmune disease: the Cambridge experience.Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 67 8
M. Noguchi, K. Matsuo, T. Hirose (1991)
Reconstruction of short nose deformity using nasolabial flaps pedicled on the infraorbital vessels.British journal of plastic surgery, 44 8
H. Song, B. Lee, Y. Jang (2008)
Processed costal cartilage homograft in rhinoplasty: the Asan Medical Center experience.Archives of otolaryngology--head & neck surgery, 134 5
O. Cakmak, I. Emre, F. Ozkurt (2015)
Identifying Septal Support Reconstructions for Saddle Nose Deformity: The Cakmak Algorithm.JAMA facial plastic surgery, 17 6
S. Gubbels, A. Barkhuizen, P. Hwang (2003)
Head and neck manifestations of Wegener's granulomatosis.Otolaryngologic clinics of North America, 36 4
D. Sherris (1997)
Caudal and Dorsal Septal Reconstruction: An Algorithm for Graft ChoicesAmerican Journal of Rhinology & Allergy, 11
C. Cingi, G. Eskiizmir, H. Çaklı (2012)
Comparative Analysis of Primary and Secondary Rhinoplasties According to Surgeon's Perspective, Patient Satisfaction, and Quality of LifeAnnals of Otology, Rhinology & Laryngology, 121
G. Rettinger (2008)
Risks and complications in rhinoplastyGMS Current Topics in Otorhinolaryngology, Head and Neck Surgery, 6
R. Daniel, Kevin Brenner (2006)
Saddle nose deformity: A new classification and treatment.Facial plastic surgery clinics of North America, 14 4
F. Duffy, R. Rossi, J. Pribaz (1998)
Reconstruction of Wegener's nasal deformity using bilateral facial artery musculomucosal flaps.Plastic and reconstructive surgery, 101 5
A. Sepehr, Ashlin Alexander, Nitin Chauhan, A. Gantous (2011)
Detailed analysis of graft techniques for nasal reconstruction following Wegener granulomatosis.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 40 6
I. Khansa, L. Khansa, Gregory Pearson (2016)
Patient Satisfaction After Rhinoplasty: A Social Media Analysis.Aesthetic surgery journal, 36 1
Donald Yoo, G. Peng, B. Azizzadeh, P. Nassif (2015)
Microbiology and antibiotic prophylaxis in rhinoplasty: a review of 363 consecutive cases.JAMA facial plastic surgery, 17 1
I. Darby, T. Hewitson (2007)
Fibroblast differentiation in wound healing and fibrosis.International review of cytology, 257
B. Schreiber, S. Twigg, J. Marais, A. Keat (2014)
Saddle-nose deformities in the rheumatology clinic.Ear, nose, & throat journal, 93 4-5
P. Vogt, A. Gohritz, M. Haubitz, A. Steiert (2011)
Reconstruction of Nasal Deformity in Wegener’s Granulomatosis: Contraindication or Benefit?Aesthetic Plastic Surgery, 35
W. Pirsig, S. Pentz, H. Lenders (1993)
Repair of saddle nose deformity in Wegener's granulomatosis and ectodermal dysplasia.Rhinology, 31 2
M. Cotch, G. Hoffman, Diane Yerg, G. Kaufman, Paul Targonski, R. Kaslow (1996)
The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources.Arthritis and rheumatism, 39 1
Jeanne Adams (1987)
Grafts and implants in nasal and chin augmentation. A rational approach to material selection.Otolaryngologic clinics of North America, 20 4
E. Csernok, W. Gross (2013)
Current understanding of the pathogenesis of granulomatosis with polyangiitis (Wegener’s)Expert Review of Clinical Immunology, 9
D. Congdon, D. Sherris, U. Specks, T. McDonald (2002)
Long‐Term Follow‐up of Repair of External Nasal Deformities in Patients With Wegener's GranulomatosisThe Laryngoscope, 112
Taha Shipchandler, B. Chung, Daniel Alam (2008)
Saddle nose deformity reconstruction with a split calvarial bone L-shaped strut.Archives of facial plastic surgery, 10 5
P. Seo (2008)
Wegener's granulomatosis: managing more than inflammationCurrent Opinion in Rheumatology, 20
N. Kesel, Dorothee Köhler, L. Herich, M. Laudien, K. Holl-Ulrich, A. Jüngel, M. Neidhart, S. Gay, R. Gay, E. Csernok, P. Lamprecht, W. Gross, U. Schumacher, S. Ullrich (2012)
Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice.The American journal of pathology, 180 5
B. Gendeh, S. Mallina (2008)
Graft selection in rinoplasty: indications and limitations.The Medical journal of Malaysia, 63 1
S. Nishiike, Takashi Kato, M. Nagai, M. Konishi, Y. Sakata (2004)
Management and Follow-up of Localized Wegener's Granulomatosis: A Review of Five CasesActa Oto-Laryngologica, 124
J. Holle, W. Gross, K. Holl-Ulrich, P. Ambrosch, B. Noelle, M. Both, E. Csernok, F. Moosig, S. Schinke, E. Reinhold-Keller (2010)
Prospective long-term follow-up of patients with localised Wegener's granulomatosis: does it occur as persistent disease stage?Annals of the Rheumatic Diseases, 69
Guy Hoffman, G. Kerr, R. Leavitt, C. Hallahan, R. Lebovics, W. Travis, M. Rottem, A. Fauci (1992)
Wegener Granulomatosis: An Analysis of 158 PatientsAnnals of Internal Medicine, 116
E. Pribitkin, W. Ezzat (2009)
Classification and treatment of the saddle nose deformity.Otolaryngologic clinics of North America, 42 3
Ali MSc, A. Gantous (2007)
The use of autogenous costal cartilage graft in septorhinoplastyOtolaryngology–Head and Neck Surgery, 137
M. Durbec, F. Disant (2014)
Saddle nose: classification and therapeutic management.European annals of otorhinolaryngology, head and neck diseases, 131 2
J. Stone (2003)
Limited versus severe Wegener's granulomatosis: baseline data on patients in the Wegener's granulomatosis etanercept trial.Arthritis and rheumatism, 48 8
M. Abboud, M. Lejour, M. Greuse (2004)
Nasal reconstruction in Wegener's diseaseEuropean Journal of Plastic Surgery, 15
S. Cannady, Pete Batra, C. Koening, Robert Lorenz, M. Citardi, C. Langford, Guy Hoffman (2009)
Sinonasal Wegener granulomatosis: A single‐institution experience with 120 casesThe Laryngoscope, 119
Yeller Demirtas, R. Yavuzer, K. Fındıkçıoğlu, K. Atabay, I. Jackson (2006)
Fixation of the Split Calvarial Graft in Nasal ReconstructionJournal of Craniofacial Surgery, 17
ImportanceRepairing the saddle nose deformity in the setting of granulomatosis with polyangiitis disease is a rare but challenging situation for any surgeon. Given that the available data in the literature is based on case reports and small case series, there is little evidence available to help delineate which reconstructive techniques are optimal. ObjectiveTo examine which techniques were most successful in reconstructive rhinoplasty for a saddle nose deformity secondary to granulomatosis with polyangiitis. Evidence ReviewPubMed, MEDLINE, Cochrane Collaboration Databases, and Web of Science were searched using the terms Wegener’s granulomatosis or granulomatosis with polyangiitis cross-referenced with saddle nose deformity or acquired nasal deformity. These databases were supplemented with 2 cases from Boston Medical Center. Databases were queried from inception of article collection through December 14, 2015, to identify publications reporting the repair of a saddle nose deformity and granulomatosis with polyangiitis. FindingsA total of 10 studies met inclusion criteria yielding a cohort of 44 patients. The overall success rate for rhinoplasty, both primary and secondary, was 84.1% (37 of 44 patients), with a complication rate of 20%. The use of a single L-shaped graft fared better than individually placed grafts. An increased risk of graft failure was noted as the number of overall grafts increased and if nonautologous tissue was used. Conclusions and RelevanceRhinoplasty for saddle nose deformity is a safe and effective procedure in the setting of granulomatosis with polyangiitis. In the face of this disease, reconstruction should focus on placing a robust, L-shaped strut graft with autologous tissue over individual grafts. Additionally, the use of split-calvarial bone appears to have a slightly lower complication rate over costal cartilage.
JAMA Otolaryngology - Head & Neck Surgery – American Medical Association
Published: May 15, 2017
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.