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Subglottic Presentation of a Rare Tumor: Primary or Metastatic?

Subglottic Presentation of a Rare Tumor: Primary or Metastatic? Clinical Review & Education Clinical Problem Solving | PATHOLOGY Subglottic Presentation of a Rare Tumor: Primary or Metastatic? Soroush Zaghi, MD; Delila Pouldar, BA; Chi Lai, MD; Dinesh K. Chhetri, MD A B C D Figure. A 66-year-old white female ex-smoker presented for evaluation laryngoscopy revealed a large, left-sided subglottic mass at the level of worsening shortness of breath and dysphagia over the course of the cricoid with approximately 70% obstruction of the subglot- of 1 week. Her medical history was notable for osteoarthritis, tic trachea. The mass extended from the left anterior cricoid to the hyperlipidemia, and gastroesophageal reflux disease. She had a posterior cricoid just inferior to the left arytenoid cartilage. 30–pack-year history of smoking cigarettes but had quit smoking The hematoxylin-eosin photomicrographs from the biopsy 20 years prior. Her social history was notable for occasionally specimen (Figure, B and C) revealed diffuse sheets and nests of epi- drinking wine. theloid cells involving the overlying markedly attenuated, nonkera- On office endoscopic examination, there was a large, left- tinizing squamous mucosa and extending into the lamina propria. sided exophytic subglottic mass at the level of the cricoid with ap- The nuclei were significantly pleomorphic with prominent macro- proximately http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Otolaryngology - Head & Neck Surgery American Medical Association

Subglottic Presentation of a Rare Tumor: Primary or Metastatic?

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References (7)

Publisher
American Medical Association
Copyright
Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6181
eISSN
2168-619X
DOI
10.1001/jamaoto.2013.3424
pmid
23868432
Publisher site
See Article on Publisher Site

Abstract

Clinical Review & Education Clinical Problem Solving | PATHOLOGY Subglottic Presentation of a Rare Tumor: Primary or Metastatic? Soroush Zaghi, MD; Delila Pouldar, BA; Chi Lai, MD; Dinesh K. Chhetri, MD A B C D Figure. A 66-year-old white female ex-smoker presented for evaluation laryngoscopy revealed a large, left-sided subglottic mass at the level of worsening shortness of breath and dysphagia over the course of the cricoid with approximately 70% obstruction of the subglot- of 1 week. Her medical history was notable for osteoarthritis, tic trachea. The mass extended from the left anterior cricoid to the hyperlipidemia, and gastroesophageal reflux disease. She had a posterior cricoid just inferior to the left arytenoid cartilage. 30–pack-year history of smoking cigarettes but had quit smoking The hematoxylin-eosin photomicrographs from the biopsy 20 years prior. Her social history was notable for occasionally specimen (Figure, B and C) revealed diffuse sheets and nests of epi- drinking wine. theloid cells involving the overlying markedly attenuated, nonkera- On office endoscopic examination, there was a large, left- tinizing squamous mucosa and extending into the lamina propria. sided exophytic subglottic mass at the level of the cricoid with ap- The nuclei were significantly pleomorphic with prominent macro- proximately

Journal

JAMA Otolaryngology - Head & Neck Surgery – American Medical Association

Published: Jul 1, 2013

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