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- Publisher
- American Medical Association
- Copyright
- Copyright 2018 American Medical Association. All Rights Reserved.
- ISSN
- 2168-6165
- eISSN
- 2168-6173
- DOI
- 10.1001/jamaophthalmol.2018.2664
- Publisher site
- See Article on Publisher Site
Abstract
Key PointsQuestionCan improvements be made in a currently used set of criteria to diagnose Vogt-Koyanagi-Harada (VKH) disease? FindingsIn a case-control study including 1257 patients, the Diagnostic Criteria for VKH Disease (DCV) were developed using latent class analysis on 634 patients with VKH disease and 623 patients with non-VKH uveitis. The DCV were compared with another set of samples containing 537 patients with definite VKH disease and 525 patients with non-VKH uveitis and showed a higher sensitivity and negative predictive value compared with the Revised Diagnostic Criteria for VKH Disease. MeaningThese results suggest that use of the DCV could result in an improvement in the sensitivity and negative predictive value to diagnose VKH disease.
Journal
JAMA Ophthalmology – American Medical Association
Published: Sep 5, 2018