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Optical Coherence Tomography Angiography Compared With Optical Coherence Tomography Macular Measurements for Detection of Glaucoma

Optical Coherence Tomography Angiography Compared With Optical Coherence Tomography Macular... Key PointsQuestionDoes optical coherence tomography angiography measurement of inner macular vessel density outperform optical coherence tomography measurement of inner macular thickness in the diagnostic evaluation of glaucoma? FindingsIn a cross-sectional study including 115 patients with glaucoma and 35 healthy individuals, at 90% specificity, the sensitivity to discriminate glaucomatous eyes from healthy eyes was 60.2% for inner macular vessel density and 81.4% for inner macular thickness. The strength of the structure-function association was stronger for inner macular thickness for both linear and nonlinear regression analyses than inner macular vessel density. MeaningThese data suggest that optical coherence tomography angiography of the macula is limited in the diagnostic evaluation of glaucoma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Optical Coherence Tomography Angiography Compared With Optical Coherence Tomography Macular Measurements for Detection of Glaucoma

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References (38)

Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/jamaophthalmol.2018.1627
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionDoes optical coherence tomography angiography measurement of inner macular vessel density outperform optical coherence tomography measurement of inner macular thickness in the diagnostic evaluation of glaucoma? FindingsIn a cross-sectional study including 115 patients with glaucoma and 35 healthy individuals, at 90% specificity, the sensitivity to discriminate glaucomatous eyes from healthy eyes was 60.2% for inner macular vessel density and 81.4% for inner macular thickness. The strength of the structure-function association was stronger for inner macular thickness for both linear and nonlinear regression analyses than inner macular vessel density. MeaningThese data suggest that optical coherence tomography angiography of the macula is limited in the diagnostic evaluation of glaucoma.

Journal

JAMA OphthalmologyAmerican Medical Association

Published: Aug 31, 2018

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