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Key PointsQuestionDoes optical coherence tomography angiography measurement of inner macular vessel density outperform optical coherence tomography measurement of inner macular thickness in the diagnostic evaluation of glaucoma? FindingsIn a cross-sectional study including 115 patients with glaucoma and 35 healthy individuals, at 90% specificity, the sensitivity to discriminate glaucomatous eyes from healthy eyes was 60.2% for inner macular vessel density and 81.4% for inner macular thickness. The strength of the structure-function association was stronger for inner macular thickness for both linear and nonlinear regression analyses than inner macular vessel density. MeaningThese data suggest that optical coherence tomography angiography of the macula is limited in the diagnostic evaluation of glaucoma.
JAMA Ophthalmology – American Medical Association
Published: Aug 31, 2018
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