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Letters Figure 2. Fundus Photographs and Optical Coherence Tomography 300 300 Above normal limits (P < .01) 240 240 180 180 Borderline above (P < .05) 120 120 Within normal limits (P < .05) 60 60 Borderline below (P < .05) 0 0 –180 –135 –90 –45 0 45 90 135 180 –180 –135 –90 –45 0 45 90 135 180 Below normal limits (P < .01) N I T S N N I T S N Position, Degrees Position, Degrees S S OD 117 130 OS T N N T 29 71 73 33 I I –180 –135 –90 –45 0 45 90 135 180 81 82 N I T S N Position, Degrees Fundus photographs demonstrate temporal disc pallor (A) and optical coherence tomography shows corresponding atrophy of the temporal peripapillary retinal nerve fiber layer (B). I indicates inferior; N, nasal; S, superior; and T, temporal. Commonwealth University, Richmond (Haines); Department of Ophthalmology, 6. Atamna H, Newberry J, Erlitzki R, Schultz CS, Ames BN. Biotin deficiency University of Iowa, Iowa City (Haines, Longmuir). inhibits heme synthesis and impairs mitochondria in human lung fibroblasts. J Nutr. 2007;137(1):25-30. Corresponding Author: Scott R. Haines, MD, Departments of Neurology and Ophthalmology,
JAMA Ophthalmology – American Medical Association
Published: Feb 1, 2014
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