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Letters SIH. MRM and CTM protocols are shown in the eTable in the Angelique Sao-Mai Sy Tay, MD Supplement. Marcel Maya, MD Results were extracted from clinical imaging reports. All Franklin G. Moser, MD, MMM discordant studies were reviewed by one neuroradiologist and Miriam Nuño, PhD one neurosurgeon, and in case of disagreement, by a second Wouter I. Schievink, MD neuroradiologist to reach consensus. Author Affiliations: Department of Neurosurgery, Cedars-Sinai Medical Center, The primary end point was the noninferiority compari- Los Angeles, California (Tay, Schievink); Department of Imaging, son of MRM and CTM. Noninferiority analysis for the pro- Cedars-Sinai Medical Center, Los Angeles, California (Maya, Moser); portion (risk) difference was based on the Farrington and Department of Public Health Sciences, University of California, Davis (Nuño). Manning likelihood score test. We considered a noninferior- Accepted for Publication: June 25, 2021. ity margin of 0.10 to be clinically meaningful. If the lower Published Online: August 30, 2021. doi:10.1001/jamaneurol.2021.2868 margin of the 90% confidence interval for difference was Corresponding Author: Wouter I. Schievink, MD, Department of Neurosurgery, more than 0.10, MRM would be considered as noninferior Cedars-Sinai Medical Center, 127 S San Vicente Blvd, Ste A6600, Los Angeles, CA 90048 (schievinkw@cshs.org). to
JAMA Neurology – American Medical Association
Published: Oct 9, 2021
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