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Agent Orange Exposure and Dementia Diagnosis in US Veterans of the Vietnam Era—Reply

Agent Orange Exposure and Dementia Diagnosis in US Veterans of the Vietnam Era—Reply Letters SIH. MRM and CTM protocols are shown in the eTable in the Angelique Sao-Mai Sy Tay, MD Supplement. Marcel Maya, MD Results were extracted from clinical imaging reports. All Franklin G. Moser, MD, MMM discordant studies were reviewed by one neuroradiologist and Miriam Nuño, PhD one neurosurgeon, and in case of disagreement, by a second Wouter I. Schievink, MD neuroradiologist to reach consensus. Author Affiliations: Department of Neurosurgery, Cedars-Sinai Medical Center, The primary end point was the noninferiority compari- Los Angeles, California (Tay, Schievink); Department of Imaging, son of MRM and CTM. Noninferiority analysis for the pro- Cedars-Sinai Medical Center, Los Angeles, California (Maya, Moser); portion (risk) difference was based on the Farrington and Department of Public Health Sciences, University of California, Davis (Nuño). Manning likelihood score test. We considered a noninferior- Accepted for Publication: June 25, 2021. ity margin of 0.10 to be clinically meaningful. If the lower Published Online: August 30, 2021. doi:10.1001/jamaneurol.2021.2868 margin of the 90% confidence interval for difference was Corresponding Author: Wouter I. Schievink, MD, Department of Neurosurgery, more than 0.10, MRM would be considered as noninferior Cedars-Sinai Medical Center, 127 S San Vicente Blvd, Ste A6600, Los Angeles, CA 90048 (schievinkw@cshs.org). to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Agent Orange Exposure and Dementia Diagnosis in US Veterans of the Vietnam Era—Reply

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References (3)

Publisher
American Medical Association
Copyright
Copyright 2021 American Medical Association. All Rights Reserved.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2021.2609
Publisher site
See Article on Publisher Site

Abstract

Letters SIH. MRM and CTM protocols are shown in the eTable in the Angelique Sao-Mai Sy Tay, MD Supplement. Marcel Maya, MD Results were extracted from clinical imaging reports. All Franklin G. Moser, MD, MMM discordant studies were reviewed by one neuroradiologist and Miriam Nuño, PhD one neurosurgeon, and in case of disagreement, by a second Wouter I. Schievink, MD neuroradiologist to reach consensus. Author Affiliations: Department of Neurosurgery, Cedars-Sinai Medical Center, The primary end point was the noninferiority compari- Los Angeles, California (Tay, Schievink); Department of Imaging, son of MRM and CTM. Noninferiority analysis for the pro- Cedars-Sinai Medical Center, Los Angeles, California (Maya, Moser); portion (risk) difference was based on the Farrington and Department of Public Health Sciences, University of California, Davis (Nuño). Manning likelihood score test. We considered a noninferior- Accepted for Publication: June 25, 2021. ity margin of 0.10 to be clinically meaningful. If the lower Published Online: August 30, 2021. doi:10.1001/jamaneurol.2021.2868 margin of the 90% confidence interval for difference was Corresponding Author: Wouter I. Schievink, MD, Department of Neurosurgery, more than 0.10, MRM would be considered as noninferior Cedars-Sinai Medical Center, 127 S San Vicente Blvd, Ste A6600, Los Angeles, CA 90048 (schievinkw@cshs.org). to

Journal

JAMA NeurologyAmerican Medical Association

Published: Oct 9, 2021

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