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- Publisher
- American Medical Association
- Copyright
- Copyright 2020 American Medical Association. All Rights Reserved.
- ISSN
- 2168-6149
- eISSN
- 2168-6157
- DOI
- 10.1001/jamaneurol.2020.0326
- Publisher site
- See Article on Publisher Site
Abstract
Key PointsQuestionDoes treatment with remote ischemic perconditioning reduce brain infarction volume growth in patients with acute ischemic stroke? FindingsIn this randomized clinical trial of 188 patients with acute ischemic stroke, brain infarction volume was used as an outcome measure. Treatment with remote ischemic perconditioning within 6 hours of symptom onset was found not to reduce brain infarction volume growth. MeaningContrary to the observations reported in preclinical studies, treatment with in-hospital remote ischemic perconditioning (in addition to reperfusion therapies) did not reduce brain infarction volume growth.
Journal
JAMA Neurology – American Medical Association
Published: Jun 30, 2020