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Effect of Dextroamphetamine on Poststroke Motor Recovery

Effect of Dextroamphetamine on Poststroke Motor Recovery Key PointsQuestionDoes the administration of dextroamphetamine combined with physiotherapy improve poststroke motor recovery? FindingsIn this pilot randomized clinical trial of 64 patients with ischemic stroke, no overall treatment-associated difference in the change in Fugl-Meyer motor scores from baseline to 3 months after treatment, no overall treatment-associated differences in any of the study’s secondary measures, and no differences in any subgroup based on stroke location or baseline severity were found. No adverse events were attributed to study treatments. MeaningThis study found no evidence that dextroamphetamine combined with physiotherapy improves poststroke motor recovery. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

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References (40)

Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2018.2338
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionDoes the administration of dextroamphetamine combined with physiotherapy improve poststroke motor recovery? FindingsIn this pilot randomized clinical trial of 64 patients with ischemic stroke, no overall treatment-associated difference in the change in Fugl-Meyer motor scores from baseline to 3 months after treatment, no overall treatment-associated differences in any of the study’s secondary measures, and no differences in any subgroup based on stroke location or baseline severity were found. No adverse events were attributed to study treatments. MeaningThis study found no evidence that dextroamphetamine combined with physiotherapy improves poststroke motor recovery.

Journal

JAMA NeurologyAmerican Medical Association

Published: Dec 27, 2018

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