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References (75)
-
T. Salthouse, R. Babcock (1991)
Decomposing adult age differences in working memory.Developmental Psychology, 27
-
T. Hedden, Hwamee Oh, Alayna Younger, Tanu Patel (2013)
Meta-analysis of amyloid-cognition relations in cognitively normal older adultsNeurology, 80
-
(Villemagne VL, Burnham S, Bourgeat P, ; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group. Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer’s disease: a prospective cohort study. Lancet Neurol. 2013;12(4):357-367.23477989)
Villemagne VL, Burnham S, Bourgeat P, ; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group. Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer’s disease: a prospective cohort study. Lancet Neurol. 2013;12(4):357-367.23477989Villemagne VL, Burnham S, Bourgeat P, ; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group. Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer’s disease: a prospective cohort study. Lancet Neurol. 2013;12(4):357-367.23477989, Villemagne VL, Burnham S, Bourgeat P, ; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group. Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer’s disease: a prospective cohort study. Lancet Neurol. 2013;12(4):357-367.23477989
-
J. Brandt (1991)
The Hopkins Verbal Learning Test: Development of a new memory test with six equivalent forms.Clinical Neuropsychologist, 5
-
S. Resnick, J. Sojkova, J. Sojkova, Yun Zhou, Y. An, W. Ye, D. Holt, R. Dannals, C. Mathis, W. Klunk, L. Ferrucci, M. Kraut, D. Wong (2010)
Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiBNeurology, 74
-
(Sperling R, Mormino E, Johnson K. The evolution of preclinical Alzheimer’s disease: implications for prevention trials. Neuron. 2014;84(3):608-622.25442939)
Sperling R, Mormino E, Johnson K. The evolution of preclinical Alzheimer’s disease: implications for prevention trials. Neuron. 2014;84(3):608-622.25442939Sperling R, Mormino E, Johnson K. The evolution of preclinical Alzheimer’s disease: implications for prevention trials. Neuron. 2014;84(3):608-622.25442939, Sperling R, Mormino E, Johnson K. The evolution of preclinical Alzheimer’s disease: implications for prevention trials. Neuron. 2014;84(3):608-622.25442939
-
V. Villemagne, V. Villemagne, S. Burnham, P. Bourgeat, B. Brown, K. Ellis, O. Salvado, C. Szoeke, S. Macaulay, Ralph Martins, P. Maruff, D. Ames, C. Rowe, C. Masters (2013)
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort studyThe Lancet Neurology, 12
-
E. Mormino, Michael Brandel, Cindee Madison, G. Rabinovici, Shawn Marks, S. Baker, W. Jagust (2012)
Not quite PIB-positive, not quite PIB-negative: Slight PIB elevations in elderly normal control subjects are biologically relevantNeuroImage, 59
-
E. Kok, S. Haikonen, T. Luoto, H. Huhtala, S. Goebeler, H. Haapasalo, P. Karhunen (2009)
Apolipoprotein E–dependent accumulation of Alzheimer disease–related lesions begins in middle ageAnnals of Neurology, 65
-
R. Sperling, E. Mormino, Keith Johnson (2014)
The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention TrialsNeuron, 84
-
E. Mormino, R. Betensky, T. Hedden, A. Schultz, R. Amariglio, D. Rentz, Keith Johnson, R. Sperling (2014)
Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals.JAMA neurology, 71 11
-
M. Jenkinson, Stephen Smith (2001)
A global optimisation method for robust affine registration of brain imagesMedical image analysis, 5 2
-
T. Robbins, M. James, A. Owen, B. Sahakian, L. McInnes, P. Rabbitt (1994)
Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers.Dementia, 5 5
-
(Rodrigue KM, Kennedy KM, Devous MD Sr, . β-Amyloid burden in healthy aging: regional distribution and cognitive consequences. Neurology. 2012;78(6):387-395.22302550)
Rodrigue KM, Kennedy KM, Devous MD Sr, . β-Amyloid burden in healthy aging: regional distribution and cognitive consequences. Neurology. 2012;78(6):387-395.22302550Rodrigue KM, Kennedy KM, Devous MD Sr, . β-Amyloid burden in healthy aging: regional distribution and cognitive consequences. Neurology. 2012;78(6):387-395.22302550, Rodrigue KM, Kennedy KM, Devous MD Sr, . β-Amyloid burden in healthy aging: regional distribution and cognitive consequences. Neurology. 2012;78(6):387-395.22302550
-
B. Fischl, M. Sereno, A. Dale (1999)
Cortical Surface-Based Analysis II: Inflation, Flattening, and a Surface-Based Coordinate SystemNeuroImage, 9
-
(Jack CR Jr, Bennett DA, Blennow K, . A/T/N: an unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. 2016;87(5):539-547.27371494)
Jack CR Jr, Bennett DA, Blennow K, . A/T/N: an unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. 2016;87(5):539-547.27371494Jack CR Jr, Bennett DA, Blennow K, . A/T/N: an unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. 2016;87(5):539-547.27371494, Jack CR Jr, Bennett DA, Blennow K, . A/T/N: an unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. 2016;87(5):539-547.27371494
-
K. Ellis, C. Rowe, C. Masters, R. Martins, P. Hudson, A. Milner, L. Bevege, D. Ames (2009)
Baseline data from the Australian Imaging Biomarkers and Lifestyle Flagship Study of AgeingAlzheimer's & Dementia, 5
-
(Lim YY, Maruff P, Pietrzak RH, ; AIBL Research Group. Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer’s disease. Brain. 2014;137(pt 1):221-231.24176981)
Lim YY, Maruff P, Pietrzak RH, ; AIBL Research Group. Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer’s disease. Brain. 2014;137(pt 1):221-231.24176981Lim YY, Maruff P, Pietrzak RH, ; AIBL Research Group. Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer’s disease. Brain. 2014;137(pt 1):221-231.24176981, Lim YY, Maruff P, Pietrzak RH, ; AIBL Research Group. Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer’s disease. Brain. 2014;137(pt 1):221-231.24176981
-
N. Savalia, Phillip Agres, Micaela Chan, E. Feczko, K. Kennedy, G. Wig (2016)
Motion‐related artifacts in structural brain images revealed with independent estimates of in‐scanner head motionHuman Brain Mapping, 38
-
K. Rodrigue, K. Kennedy, M. Devous, J. Rieck, A. Hebrank, Ramon Diaz‐Arrastia, D. Mathews, Denise Park, Denise Park (2012)
&bgr;-Amyloid burden in healthy aging: Regional distribution and cognitive consequencesNeurology, 78
-
R. Sperling, P. Aisen, L. Beckett, D. Bennett, S. Craft, A. Fagan, T. Iwatsubo, C. Jack, J. Kaye, T. Montine, Denise Park, E. Reiman, C. Rowe, E. Siemers, Y. Stern, K. Yaffe, M. Carrillo, B. Thies, M. Morrison‐Bogorad, M. Wagster, C. Phelps (2011)
Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseAlzheimer's & Dementia, 7
-
(Brandt J. The Hopkins verbal learning test: development of a new memory test with six equivalent forms. Clin Neuropsychol. 1991;5(2):125-142. dx.doi.org/10.1080/13854049108403297)
Brandt J. The Hopkins verbal learning test: development of a new memory test with six equivalent forms. Clin Neuropsychol. 1991;5(2):125-142. dx.doi.org/10.1080/13854049108403297Brandt J. The Hopkins verbal learning test: development of a new memory test with six equivalent forms. Clin Neuropsychol. 1991;5(2):125-142. dx.doi.org/10.1080/13854049108403297, Brandt J. The Hopkins verbal learning test: development of a new memory test with six equivalent forms. Clin Neuropsychol. 1991;5(2):125-142. dx.doi.org/10.1080/13854049108403297
-
(Wirth M, Oh H, Mormino EC, Markley C, Landau SM, Jagust WJ. The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly. Alzheimers Dement. 2013;9(6):687-698.e1.23474040)
Wirth M, Oh H, Mormino EC, Markley C, Landau SM, Jagust WJ. The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly. Alzheimers Dement. 2013;9(6):687-698.e1.23474040Wirth M, Oh H, Mormino EC, Markley C, Landau SM, Jagust WJ. The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly. Alzheimers Dement. 2013;9(6):687-698.e1.23474040, Wirth M, Oh H, Mormino EC, Markley C, Landau SM, Jagust WJ. The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly. Alzheimers Dement. 2013;9(6):687-698.e1.23474040
-
Hwamee Oh, E. Mormino, Cindee Madison, Amynta Hayenga, Andre Smiljic, W. Jagust (2011)
β-Amyloid affects frontal and posterior brain networks in normal agingNeuroImage, 54
-
(2011)
workgroupsondiagnosticguidelinesforAlzheimer’sdisease -
D. Rentz, J. Locascio, J. Becker, E. Moran, Elisha Eng, R. Buckner, R. Sperling, Keith Johnson (2009)
Cognition, Reserve, and Amyloid Deposition in Normal AgingAnnals of Neurology, 67
-
Y. Lim, P. Maruff, R. Pietrzak, D. Ames, K. Ellis, K. Harrington, N. Lautenschlager, C. Szoeke, R. Martins, C. Masters, V. Villemagne, C. Rowe (2014)
Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease.Brain : a journal of neurology, 137 Pt 1
-
Y. Lim, R. Pietrzak, K. Ellis, J. Jaeger, K. Harrington, T. Ashwood, C. Szoeke, R. Martins, A. Bush, C. Masters, C. Rowe, V. Villemagne, D. Ames, D. Darby, P. Maruff (2013)
Rapid decline in episodic memory in healthy older adults with high amyloid-β.Journal of Alzheimer's disease : JAD, 33 3
-
(Petersen RC, Wiste HJ, Weigand SD, . Association of elevated amyloid levels with cognition and biomarkers in cognitively normal people from the community. JAMA Neurol. 2016;73(1):85-92.26595683)
Petersen RC, Wiste HJ, Weigand SD, . Association of elevated amyloid levels with cognition and biomarkers in cognitively normal people from the community. JAMA Neurol. 2016;73(1):85-92.26595683Petersen RC, Wiste HJ, Weigand SD, . Association of elevated amyloid levels with cognition and biomarkers in cognitively normal people from the community. JAMA Neurol. 2016;73(1):85-92.26595683, Petersen RC, Wiste HJ, Weigand SD, . Association of elevated amyloid levels with cognition and biomarkers in cognitively normal people from the community. JAMA Neurol. 2016;73(1):85-92.26595683
-
(Schott JM, Bartlett JW, Fox NC, Barnes J; Alzheimer’s Disease Neuroimaging Initiative Investigators. Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42. Ann Neurol. 2010;68(6):825-834.21181717)
Schott JM, Bartlett JW, Fox NC, Barnes J; Alzheimer’s Disease Neuroimaging Initiative Investigators. Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42. Ann Neurol. 2010;68(6):825-834.21181717Schott JM, Bartlett JW, Fox NC, Barnes J; Alzheimer’s Disease Neuroimaging Initiative Investigators. Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42. Ann Neurol. 2010;68(6):825-834.21181717, Schott JM, Bartlett JW, Fox NC, Barnes J; Alzheimer’s Disease Neuroimaging Initiative Investigators. Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42. Ann Neurol. 2010;68(6):825-834.21181717
-
G. Chételat, V. Villemagne, Nicolas Villain, G. Jones, K. Ellis, D. Ames, R. Martins, C. Masters, C. Rowe (2012)
Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid depositionNeurology, 78
-
R. Desikan, F. Ségonne, B. Fischl, B. Quinn, B. Dickerson, D. Blacker, R. Buckner, A. Dale, R. Maguire, B. Hyman, M. Albert, R. Killiany (2006)
An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interestNeuroImage, 31
-
C. Jack, D. Bennett, K. Blennow, M. Carrillo, H. Feldman, G. Frisoni, H. Hampel, W. Jagust, Keith Johnson, D. Knopman, R. Petersen, P. Scheltens, R. Sperling, B. Dubois (2016)
A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkersNeurology, 87
-
(Mormino EC, Betensky RA, Hedden T, . Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. JAMA Neurol. 2014;71(11):1379-1385.25222039)
Mormino EC, Betensky RA, Hedden T, . Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. JAMA Neurol. 2014;71(11):1379-1385.25222039Mormino EC, Betensky RA, Hedden T, . Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. JAMA Neurol. 2014;71(11):1379-1385.25222039, Mormino EC, Betensky RA, Hedden T, . Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. JAMA Neurol. 2014;71(11):1379-1385.25222039
-
(Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal. 2001;5(2):143-156.11516708)
Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal. 2001;5(2):143-156.11516708Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal. 2001;5(2):143-156.11516708, Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal. 2001;5(2):143-156.11516708
-
(Salthouse TA, Babcock RL. Decomposing adult age-differences in working memory. Dev Psychol. 1991;27(5):763-776. dx.doi.org/10.1037/0012-1649.27.5.763)
Salthouse TA, Babcock RL. Decomposing adult age-differences in working memory. Dev Psychol. 1991;27(5):763-776. dx.doi.org/10.1037/0012-1649.27.5.763Salthouse TA, Babcock RL. Decomposing adult age-differences in working memory. Dev Psychol. 1991;27(5):763-776. dx.doi.org/10.1037/0012-1649.27.5.763, Salthouse TA, Babcock RL. Decomposing adult age-differences in working memory. Dev Psychol. 1991;27(5):763-776. dx.doi.org/10.1037/0012-1649.27.5.763
-
T. Hedden, Denise Park, R. Nisbett, L. Ji, Q. Jing, S. Jiao (2002)
Cultural variation in verbal versus spatial neuropsychological function across the life span.Neuropsychology, 16 1
-
(Savalia NK, Agres PF, Chan MY, Feczko EJ, Kennedy KM, Wig GS. Motion-related artifacts in structural brain images revealed with independent estimates of in-scanner head motion. Hum Brain Mapp. 2017;38(1):472-492.27634551)
Savalia NK, Agres PF, Chan MY, Feczko EJ, Kennedy KM, Wig GS. Motion-related artifacts in structural brain images revealed with independent estimates of in-scanner head motion. Hum Brain Mapp. 2017;38(1):472-492.27634551Savalia NK, Agres PF, Chan MY, Feczko EJ, Kennedy KM, Wig GS. Motion-related artifacts in structural brain images revealed with independent estimates of in-scanner head motion. Hum Brain Mapp. 2017;38(1):472-492.27634551, Savalia NK, Agres PF, Chan MY, Feczko EJ, Kennedy KM, Wig GS. Motion-related artifacts in structural brain images revealed with independent estimates of in-scanner head motion. Hum Brain Mapp. 2017;38(1):472-492.27634551
-
(Kennedy KM, Rodrigue KM, Devous MD Sr, Hebrank AC, Bischof GN, Park DC. Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan. Neuroimage. 2012;62(1):1-8.22569063)
Kennedy KM, Rodrigue KM, Devous MD Sr, Hebrank AC, Bischof GN, Park DC. Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan. Neuroimage. 2012;62(1):1-8.22569063Kennedy KM, Rodrigue KM, Devous MD Sr, Hebrank AC, Bischof GN, Park DC. Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan. Neuroimage. 2012;62(1):1-8.22569063, Kennedy KM, Rodrigue KM, Devous MD Sr, Hebrank AC, Bischof GN, Park DC. Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan. Neuroimage. 2012;62(1):1-8.22569063
-
Philip Insel, N. Mattsson, R. Mackin, M. Schöll, R. Nosheny, D. Tosun, M. Donohue, P. Aisen, W. Jagust, M. Weiner (2016)
Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathologyNeurology, 86
-
R. Petersen, H. Wiste, S. Weigand, W. Rocca, R. Roberts, M. Mielke, V. Lowe, D. Knopman, V. Pankratz, M. Machulda, Y. Geda, C. Jack (2016)
Association of Elevated Amyloid Levels With Cognition and Biomarkers in Cognitively Normal People From the Community.JAMA neurology, 73 1
-
(Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system. Neuroimage. 1999;9(2):195-207.9931269)
Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system. Neuroimage. 1999;9(2):195-207.9931269Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system. Neuroimage. 1999;9(2):195-207.9931269, Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system. Neuroimage. 1999;9(2):195-207.9931269
-
H. Aizenstein, R. Nebes, J. Saxton, J. Price, C. Mathis, N. Tsopelas, S. Ziolko, Jeffrey James, B. Snitz, P. Houck, W. Bi, A. Cohen, B. Lopresti, S. DeKosky, E. Halligan, W. Klunk (2008)
Frequent amyloid deposition without significant cognitive impairment among the elderly.Archives of neurology, 65 11
-
J. Schott, J. Bartlett, Nick Fox, J. Barnes (2010)
Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1‐42Annals of Neurology, 68
-
(Chételat G, Villemagne VL, Villain N, ; AIBL Research Group. Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition. Neurology. 2012;78(7):477-484.22302548)
Chételat G, Villemagne VL, Villain N, ; AIBL Research Group. Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition. Neurology. 2012;78(7):477-484.22302548Chételat G, Villemagne VL, Villain N, ; AIBL Research Group. Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition. Neurology. 2012;78(7):477-484.22302548, Chételat G, Villemagne VL, Villain N, ; AIBL Research Group. Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition. Neurology. 2012;78(7):477-484.22302548
-
(Rentz DM, Locascio JJ, Becker JA, . Cognition, reserve, and amyloid deposition in normal aging. Ann Neurol. 2010;67(3):353-364.20373347)
Rentz DM, Locascio JJ, Becker JA, . Cognition, reserve, and amyloid deposition in normal aging. Ann Neurol. 2010;67(3):353-364.20373347Rentz DM, Locascio JJ, Becker JA, . Cognition, reserve, and amyloid deposition in normal aging. Ann Neurol. 2010;67(3):353-364.20373347, Rentz DM, Locascio JJ, Becker JA, . Cognition, reserve, and amyloid deposition in normal aging. Ann Neurol. 2010;67(3):353-364.20373347
-
(Wechsler D. Wechsler Adult Intelligence Scale–III (WAIS-III). New York, NY: Psychological Corporation; 1997.)
Wechsler D. Wechsler Adult Intelligence Scale–III (WAIS-III). New York, NY: Psychological Corporation; 1997.Wechsler D. Wechsler Adult Intelligence Scale–III (WAIS-III). New York, NY: Psychological Corporation; 1997., Wechsler D. Wechsler Adult Intelligence Scale–III (WAIS-III). New York, NY: Psychological Corporation; 1997.
-
K. Pike, K. Ellis, V. Villemagne, Norm Good, G. Chételat, D. Ames, C. Szoeke, S. Laws, G. Verdile, R. Martins, C. Masters, C. Rowe (2011)
Cognition and beta-amyloid in preclinical Alzheimer's disease: Data from the AIBL studyNeuropsychologia, 49
-
(Resnick SM, Sojkova J, Zhou Y, . Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB. Neurology. 2010;74(10):807-815.20147655)
Resnick SM, Sojkova J, Zhou Y, . Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB. Neurology. 2010;74(10):807-815.20147655Resnick SM, Sojkova J, Zhou Y, . Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB. Neurology. 2010;74(10):807-815.20147655, Resnick SM, Sojkova J, Zhou Y, . Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB. Neurology. 2010;74(10):807-815.20147655
-
(Rolstad S, Berg AI, Bjerke M, . Amyloid-β42 is associated with cognitive impairment in healthy elderly and subjective cognitive impairment. J Alzheimers Dis. 2011;26(1):135-142.21593572)
Rolstad S, Berg AI, Bjerke M, . Amyloid-β42 is associated with cognitive impairment in healthy elderly and subjective cognitive impairment. J Alzheimers Dis. 2011;26(1):135-142.21593572Rolstad S, Berg AI, Bjerke M, . Amyloid-β42 is associated with cognitive impairment in healthy elderly and subjective cognitive impairment. J Alzheimers Dis. 2011;26(1):135-142.21593572, Rolstad S, Berg AI, Bjerke M, . Amyloid-β42 is associated with cognitive impairment in healthy elderly and subjective cognitive impairment. J Alzheimers Dis. 2011;26(1):135-142.21593572
-
E. Mormino, R. Betensky, T. Hedden, A. Schultz, Andrew Ward, W. Huijbers, D. Rentz, Keith Johnson, R. Sperling (2014)
Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer diseaseNeurology, 82
-
(1996)
Standard Progressive Matrices: Sets A -
Association of elevated amyloid levels with Association of Longitudinal Cognitive Decline With Baseline Amyloid Burden Original Investigation Research jamaneurology.com (Reprinted) JAMA Neurology -
(Oh H, Mormino EC, Madison C, Hayenga A, Smiljic A, Jagust WJ. β-Amyloid affects frontal and posterior brain networks in normal aging. Neuroimage. 2011;54(3):1887-1895.20965254)
Oh H, Mormino EC, Madison C, Hayenga A, Smiljic A, Jagust WJ. β-Amyloid affects frontal and posterior brain networks in normal aging. Neuroimage. 2011;54(3):1887-1895.20965254Oh H, Mormino EC, Madison C, Hayenga A, Smiljic A, Jagust WJ. β-Amyloid affects frontal and posterior brain networks in normal aging. Neuroimage. 2011;54(3):1887-1895.20965254, Oh H, Mormino EC, Madison C, Hayenga A, Smiljic A, Jagust WJ. β-Amyloid affects frontal and posterior brain networks in normal aging. Neuroimage. 2011;54(3):1887-1895.20965254
-
(Desikan RS, Ségonne F, Fischl B, . An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006;31(3):968-980.16530430)
Desikan RS, Ségonne F, Fischl B, . An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006;31(3):968-980.16530430Desikan RS, Ségonne F, Fischl B, . An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006;31(3):968-980.16530430, Desikan RS, Ségonne F, Fischl B, . An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006;31(3):968-980.16530430
-
M. Wirth, Hwamee Oh, E. Mormino, C. Markley, S. Landau, W. Jagust (2013)
The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderlyAlzheimer's & Dementia, 9
-
E. Mormino, J. Kluth, Cindee Madison, G. Rabinovici, G. Rabinovici, G. Rabinovici, S. Baker, B. Miller, R. Koeppe, C. Mathis, M. Weiner, W. Jagust, W. Jagust, W. Jagust (2009)
Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects.Brain : a journal of neurology, 132 Pt 5
-
(Aizenstein HJ, Nebes RD, Saxton JA, . Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65(11):1509-1517.19001171)
Aizenstein HJ, Nebes RD, Saxton JA, . Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65(11):1509-1517.19001171Aizenstein HJ, Nebes RD, Saxton JA, . Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65(11):1509-1517.19001171, Aizenstein HJ, Nebes RD, Saxton JA, . Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65(11):1509-1517.19001171
-
(Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P. Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia. 1994;5(5):266-281.7951684)
Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P. Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia. 1994;5(5):266-281.7951684Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P. Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia. 1994;5(5):266-281.7951684, Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P. Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia. 1994;5(5):266-281.7951684
-
(Insel PS, Mattsson N, Mackin RS, ; Alzheimer’s Disease Neuroimaging Initiative. Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology. Neurology. 2016;86(20):1887-1896.27164667)
Insel PS, Mattsson N, Mackin RS, ; Alzheimer’s Disease Neuroimaging Initiative. Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology. Neurology. 2016;86(20):1887-1896.27164667Insel PS, Mattsson N, Mackin RS, ; Alzheimer’s Disease Neuroimaging Initiative. Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology. Neurology. 2016;86(20):1887-1896.27164667, Insel PS, Mattsson N, Mackin RS, ; Alzheimer’s Disease Neuroimaging Initiative. Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology. Neurology. 2016;86(20):1887-1896.27164667
-
(Kok E, Haikonen S, Luoto T, . Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age. Ann Neurol. 2009;65(6):650-657.19557866)
Kok E, Haikonen S, Luoto T, . Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age. Ann Neurol. 2009;65(6):650-657.19557866Kok E, Haikonen S, Luoto T, . Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age. Ann Neurol. 2009;65(6):650-657.19557866, Kok E, Haikonen S, Luoto T, . Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age. Ann Neurol. 2009;65(6):650-657.19557866
-
A. Dale, B. Fischl, M. Sereno (1999)
Cortical Surface-Based Analysis I. Segmentation and Surface ReconstructionNeuroImage, 9
-
(Hedden T, Park DC, Nisbett R, Ji LJ, Jing Q, Jiao S. Cultural variation in verbal versus spatial neuropsychological function across the life span. Neuropsychology. 2002;16(1):65-73.11853358)
Hedden T, Park DC, Nisbett R, Ji LJ, Jing Q, Jiao S. Cultural variation in verbal versus spatial neuropsychological function across the life span. Neuropsychology. 2002;16(1):65-73.11853358Hedden T, Park DC, Nisbett R, Ji LJ, Jing Q, Jiao S. Cultural variation in verbal versus spatial neuropsychological function across the life span. Neuropsychology. 2002;16(1):65-73.11853358, Hedden T, Park DC, Nisbett R, Ji LJ, Jing Q, Jiao S. Cultural variation in verbal versus spatial neuropsychological function across the life span. Neuropsychology. 2002;16(1):65-73.11853358
-
K. Kennedy, K. Rodrigue, M. Devous, A. Hebrank, G. Bischof, Denise Park (2012)
Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespanNeuroImage, 62
-
Ruth Ekstrom, J. French, H. Harman (1976)
Manual for kit of factor-referenced cognitive tests -
S. Rolstad, A. Berg, M. Bjerke, K. Blennow, B. Johansson, H. Zetterberg, A. Wallin (2011)
Amyloid-β₄₂ is associated with cognitive impairment in healthy elderly and subjective cognitive impairment.Journal of Alzheimer's disease : JAD, 26 1
-
(Pike KE, Ellis KA, Villemagne VL, . Cognition and beta-amyloid in preclinical Alzheimer’s disease: data from the AIBL study. Neuropsychologia. 2011;49(9):2384-2390.21529702)
Pike KE, Ellis KA, Villemagne VL, . Cognition and beta-amyloid in preclinical Alzheimer’s disease: data from the AIBL study. Neuropsychologia. 2011;49(9):2384-2390.21529702Pike KE, Ellis KA, Villemagne VL, . Cognition and beta-amyloid in preclinical Alzheimer’s disease: data from the AIBL study. Neuropsychologia. 2011;49(9):2384-2390.21529702, Pike KE, Ellis KA, Villemagne VL, . Cognition and beta-amyloid in preclinical Alzheimer’s disease: data from the AIBL study. Neuropsychologia. 2011;49(9):2384-2390.21529702
-
(Ekstrom RB, Harman HH. Manual for Kit of Factor-Referenced Cognitive Tests, 1976. Princeton, NJ: Educational Testing Service; 1976.)
Ekstrom RB, Harman HH. Manual for Kit of Factor-Referenced Cognitive Tests, 1976. Princeton, NJ: Educational Testing Service; 1976.Ekstrom RB, Harman HH. Manual for Kit of Factor-Referenced Cognitive Tests, 1976. Princeton, NJ: Educational Testing Service; 1976., Ekstrom RB, Harman HH. Manual for Kit of Factor-Referenced Cognitive Tests, 1976. Princeton, NJ: Educational Testing Service; 1976.
-
(Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. segmentation and surface reconstruction. Neuroimage. 1999;9(2):179-194.9931268)
Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. segmentation and surface reconstruction. Neuroimage. 1999;9(2):179-194.9931268Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. segmentation and surface reconstruction. Neuroimage. 1999;9(2):179-194.9931268, Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. segmentation and surface reconstruction. Neuroimage. 1999;9(2):179-194.9931268
-
C. Jack, D. Knopman, W. Jagust, L. Shaw, P. Aisen, M. Weiner, R. Petersen, J. Trojanowski (2010)
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascadeThe Lancet Neurology, 9
-
(Raven JC. Standard Progressive Matrices: Sets A, B, C, D & E. Oxford, England: Oxford Psychologists Press; 1996.)
Raven JC. Standard Progressive Matrices: Sets A, B, C, D & E. Oxford, England: Oxford Psychologists Press; 1996.Raven JC. Standard Progressive Matrices: Sets A, B, C, D & E. Oxford, England: Oxford Psychologists Press; 1996., Raven JC. Standard Progressive Matrices: Sets A, B, C, D & E. Oxford, England: Oxford Psychologists Press; 1996.
-
S. Villeneuve, G. Rabinovici, Brendan Cohn-Sheehy, Cindee Madison, Nagehan Ayakta, P. Ghosh, R. Joie, S. Arthur-Bentil, J. Vogel, Shawn Marks, M. Lehmann, H. Rosen, B. Reed, J. Olichney, A. Boxer, B. Miller, E. Borys, Lee‐way Jin, E. Huang, L. Grinberg, C. DeCarli, W. Seeley, W. Jagust (2015)
Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation.Brain : a journal of neurology, 138 Pt 7
-
Daisuke Yamamoto, H. Kazui, M. Takeda (2011)
[Wechsler Adult Intelligence Scale-III (WAIS-III)].Nihon rinsho. Japanese journal of clinical medicine, 69 Suppl 8
-
(Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, . Existing Pittsburgh compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015;138(pt 7):2020-2033.25953778)
Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, . Existing Pittsburgh compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015;138(pt 7):2020-2033.25953778Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, . Existing Pittsburgh compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015;138(pt 7):2020-2033.25953778, Villeneuve S, Rabinovici GD, Cohn-Sheehy BI, . Existing Pittsburgh compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. Brain. 2015;138(pt 7):2020-2033.25953778
-
S. Keihaninejad, R. Heckemann, Gianlorenzo Fagiolo, M. Symms, Joseph Hajnal, A. Hammers (2010)
A robust method to estimate the intracranial volume across MRI field strengths (1.5T and 3T)Neuroimage, 50
- Publisher
- American Medical Association
- Copyright
- Copyright 2017 Farrell ME et al. JAMA Neurology.
- ISSN
- 2168-6149
- eISSN
- 2168-6157
- DOI
- 10.1001/jamaneurol.2017.0892
- pmid
- 28558099
- Publisher site
- See Article on Publisher Site
Abstract
Key PointsQuestionIs there a dose-response relationship between the magnitude of amyloid burden and the rate of cognitive decline among healthy middle-aged and older adults? FindingIn this longitudinal cohort study, healthy adults aged 40 to 89 years were assessed with 18F florbetapir positron emission tomography imaging at baseline and cognitive measures at baseline and 4-year follow-up. Increasing baseline amyloid burden predicted a steeper decline in episodic memory, processing speed, vocabulary, and Mini-Mental State Examination performance. MeaningThe initial magnitude of amyloid deposition in healthy adults may be associated with the rate of future cognitive decline and provides important information that is lost when only dichotomous information (positive/negative) is provided.
Journal
JAMA Neurology – American Medical Association
Published: Jul 30, 2017