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Association Between Serum Calcium Level and the Size and Expansion of Intracerebral Hemorrhage

Association Between Serum Calcium Level and the Size and Expansion of Intracerebral Hemorrhage Opinion EDITORIAL Association Between Serum Calcium Level and the Size and Expansion of Intracerebral Hemorrhage Mark J. Alberts, MD; Ravi Sarode, MD Intracerebral hemorrhage (ICH) is a common and deadly type elevated blood pressure, which could cause increased bleed- of stroke, with high rates of morbidity and mortality (40%- ing and increase the risk of hematoma expansion. They dis- 1,2 50% in most series). There are several well-described and count this mechanism because their study cohort did not show validated risk factors and dis- a link between blood pressure on admission and hematoma eases that increase the risk of size. Furthermore, the volume of a deep hemorrhage (which ICH, including race, hyper- is typically related to hypertension) is not related to a low cal- Related article page 1285 tension, use of anticoagu- cium level. Other studies have failed to find an association be- lants, amyloid angiopathy, renal insufficiency, thrombolytic tween blood pressure and ICH expansion. We would also dis- therapy, and drug abuse. However, not all ICHs are associ- count a relationship between calcium level, blood pressure, ated with one of these risk factors. This suggests that there and ICH status because small cerebral vessels are typically un- might http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Neurology American Medical Association

Association Between Serum Calcium Level and the Size and Expansion of Intracerebral Hemorrhage

JAMA Neurology , Volume 73 (11) – Nov 6, 2016

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References (14)

Publisher
American Medical Association
Copyright
Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6149
eISSN
2168-6157
DOI
10.1001/jamaneurol.2016.3070
pmid
27598439
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Association Between Serum Calcium Level and the Size and Expansion of Intracerebral Hemorrhage Mark J. Alberts, MD; Ravi Sarode, MD Intracerebral hemorrhage (ICH) is a common and deadly type elevated blood pressure, which could cause increased bleed- of stroke, with high rates of morbidity and mortality (40%- ing and increase the risk of hematoma expansion. They dis- 1,2 50% in most series). There are several well-described and count this mechanism because their study cohort did not show validated risk factors and dis- a link between blood pressure on admission and hematoma eases that increase the risk of size. Furthermore, the volume of a deep hemorrhage (which ICH, including race, hyper- is typically related to hypertension) is not related to a low cal- Related article page 1285 tension, use of anticoagu- cium level. Other studies have failed to find an association be- lants, amyloid angiopathy, renal insufficiency, thrombolytic tween blood pressure and ICH expansion. We would also dis- therapy, and drug abuse. However, not all ICHs are associ- count a relationship between calcium level, blood pressure, ated with one of these risk factors. This suggests that there and ICH status because small cerebral vessels are typically un- might

Journal

JAMA NeurologyAmerican Medical Association

Published: Nov 6, 2016

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